Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 10/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8132140 | 0.90 | P2RX7 (0.41) | P2RX7 | |
| SCHEMBL4438657 | 0.88 | P2RX7 (0.46) | P2RX7 | |
| SCHEMBL8134392 | 0.88 | P2RX7 (0.42) | P2RX7 | |
| SCHEMBL28785677 | 0.79 | P2RX7 (0.48) | P2RX7 | |
| SCHEMBL28785678 | 0.79 | P2RX7 (0.48) | P2RX7 | |
| SCHEMBL4448219 | 0.76 | P2RX7 (0.47) | P2RX7 | |
| SCHEMBL307024 | 0.76 | P2RX7 (0.49) | P2RX7 | |
| SCHEMBL307857 | 0.76 | P2RX7 (0.50) | P2RX7 | |
| SCHEMBL306194 | 0.76 | P2RX7 (0.43) | P2RX7 | |
| SCHEMBL306195 | 0.76 | P2RX7 (0.43) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008112205-A1 | BICYCLOHETEROARYL COMPOUNDS AS P2X7 MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2008-09-18 | — | — | WO | disclosed |