Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 6/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 6/20 | 0.47 |
| ▸ | F10 | P00742 | 10/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7119637 | 0.79 | ITGB3 (0.47) | ITGB3PRSS1PRSS2ITGA2BPRSS3 | |
| SCHEMBL7128273 | 0.78 | ITGB3 (0.44) | ITGB3PRSS1PRSS2ITGA2BPRSS3 | |
| SCHEMBL8125773 | 0.77 | F10 (0.42) | ITGB3PRSS1PRSS2ITGA2BPRSS3 | |
| SCHEMBL8124896 | 0.77 | F10 (0.41) | ITGB3PRSS1PRSS2ITGA2BPRSS3 | |
| SCHEMBL8125506 | 0.77 | MAOA (0.42) | ITGB3PRSS1PRSS2ITGA2BPRSS3 | |
| SCHEMBL8138896 | 0.76 | F10 (0.41) | ITGB3PRSS1PRSS2ITGA2BPRSS3 | |
| SCHEMBL7125767 | 0.75 | F10 (0.41) | ITGB3PRSS1PRSS2ITGA2BPRSS3 | |
| SCHEMBL8126832 | 0.75 | F10 (0.41) | ITGB3PRSS1PRSS2ITGA2BPRSS3 | |
| SCHEMBL8135588 | 0.75 | F10 (0.41) | ITGB3PRSS1PRSS2ITGA2BPRSS3 | |
| SCHEMBL13298924 | 0.74 | MAOA (0.61) | F10ABCB11MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1005468-A1 | ANTIBIOTIC OXAZOLIDINONE DERIVATIVES | ZENECA LIMITED (GB) | 2000-06-07 | — | — | EP | disclosed |
| WO-1999010342-A1 | ANTIBIOTIC OXAZOLIDINONE DERIVATIVES | ZENECA LIMITED (GB) | 1999-03-04 | — | — | WO | disclosed |