Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK2 | P53671 | 3/20 | 0.42 |
| ▸ | HTR6 | P50406 | 3/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.39 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP7 | P09237 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4682303 | 0.99 | LIMK2 (0.42) | LIMK2HTR6PTGESALDH1A1SMN1; SMN2 | |
| SCHEMBL8131416 | 0.91 | CYP2D6 (0.41) | ALDH1A1CYP2D6 | |
| Hydrochloric Acid SCHEMBL4683181 | 0.90 | CYP2D6 (0.40) | ALDH1A1CYP2D6 | |
| SCHEMBL8129128 | 0.88 | HTT (0.40) | ALDH1A1SMN1; SMN2KMT2APOLB | |
| Hydrochloric Acid SCHEMBL4682452 | 0.87 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2POLB | |
| Hydrochloric Acid SCHEMBL4683407 | 0.85 | NPC1 (0.44) | ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL4682972 | 0.83 | PPARA (0.40) | ALDH1A1SMN1; SMN2KMT2APOLB | |
| SCHEMBL4685066 | 0.83 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL4685801 | 0.83 | ACKR3 (0.44) | ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL8123903 | 0.83 | KCNH2 (0.38) | SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1058680-A1 | 2-ARYLETHYL-(PIPERIDIN-4-YLMETHYL)AMINE DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2000-12-13 | — | — | EP | disclosed |
| WO-1999043657-A1 | 2-ARYLETHYL-(PIPERIDIN-4-YLMETHYL)AMINE DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 1999-09-02 | — | — | WO | disclosed |