Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | F2R | P25116 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.38 |
| ▸ | MTOR | P42345 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4682452 | 0.99 | ALDH1A1 (0.40) | HTTALDH1A1HPGDTP53FAAH | |
| Hydrochloric Acid SCHEMBL4683407 | 0.92 | NPC1 (0.44) | ALDH1A1HPGDFAAHMAPTNPC1 | |
| SCHEMBL4682972 | 0.90 | PPARA (0.40) | ALDH1A1HPGDTP53NPC1LMNA | |
| SCHEMBL4682514 | 0.89 | LMNA (0.42) | HTTALDH1A1HPGDTP53MAPT | |
| Trifluoroacetic Acid SCHEMBL4679650 | 0.89 | UBE2M (0.38) | F2REPHX2MAPTLMNASMN1; SMN2 | |
| SCHEMBL4678644 | 0.88 | CYP2C19 (0.41) | ALDH1A1TP53MAPTNPC1LMNA | |
| Hydrochloric Acid SCHEMBL4680064 | 0.88 | SMN1; SMN2 (0.46) | ALDH1A1HPGDEPHX2LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4683526 | 0.88 | SMN1; SMN2 (0.46) | ALDH1A1HPGDEPHX2LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4680070 | 0.88 | SMN1; SMN2 (0.46) | ALDH1A1HPGDEPHX2LMNASMN1; SMN2 | |
| SCHEMBL8133252 | 0.88 | LIMK2 (0.42) | ALDH1A1SMN1; SMN2POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1058680-A1 | 2-ARYLETHYL-(PIPERIDIN-4-YLMETHYL)AMINE DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2000-12-13 | — | — | EP | disclosed |
| WO-1999043657-A1 | 2-ARYLETHYL-(PIPERIDIN-4-YLMETHYL)AMINE DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 1999-09-02 | — | — | WO | disclosed |