SCHEMBL813336

SCHEMBL813336

O=C(I)c1cccc(C(=O)I)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.52
ATM Q13315 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
PKM P14618 1/20 0.45
PARP1 P09874 3/20 0.44
THRB P10828 1/20 0.43
CES2 O00748 2/20 0.42
CES1 P23141 2/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA6 P23280 1/20 0.42
CA9 Q16790 1/20 0.42
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
DAO P14920 1/20 0.41
TSHR P16473 1/20 0.41
NAPRT Q6XQN6 1/20 0.41
ALDH1A1 P00352 1/20 0.41
FURIN P09958 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3356289 0.90 CA12 (0.58) L3MBTL1ATMTDP1PKMCA12
SCHEMBL25976299 0.88 PARP1 (0.63) L3MBTL1ATMTDP1PARP1TSHR
SCHEMBL19308082 0.88 ALDH1A1 (0.50) L3MBTL1ATMTDP1ALDH1A1HPGD
SCHEMBL18560037 0.83 PBRM1 (0.61) TDP1PARP1CA12CA1CA2
SCHEMBL19157830 0.83 PARP1 (0.63) L3MBTL1ATMPARP1TSHRALDH1A1
SCHEMBL6113180 0.83 PARP1 (0.63) TDP1PARP1HDAC8HDAC6HPGD
SCHEMBL672981 0.81
SCHEMBL4952307 0.81 PRSS1 (0.48) CA1CA2CA9
SCHEMBL3183335 0.81 TPMT (0.36) L3MBTL1ATMTDP1PKMCES2
SCHEMBL15457760 0.79 UNG (0.68) ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9346023-B2 Flux enhancing agent for improving composite polyamide reverse osmosis membrane performance GENERAL ELECTRIC COMPANY (US) 2016-05-24 US claimed
EP-2888030-A1 AMINO-SILOXANE FLUX ENHANCING AGENT FOR IMPROVING COMPOSITE POLYAMIDE REVERSE!OSMOSIS MEMBRANE PERFORMANCE General Electric Company (US) 2015-07-01 EP claimed
US-20140054228-A1 Novel Flux Enhancing Agent for Improving Composite Polyamide Reverse Osmosis Membrane Performance GENERAL ELECTRIC COMPANY (US) 2014-02-27 US claimed
WO-2014031271-A1 AMINO-SILOXANE FLUX ENHANCING AGENT FOR IMPROVING COMPOSITE POLYAMIDE REVERSE|OSMOSIS MEMBRANE PERFORMANCE GENERAL ELECTRIC COMPANY (US) 2014-02-27 WO claimed
EP-3910003-A1 POLYAMIDE-IMIDE BLOCK COPOLYMER, METHOD FOR PREPARING SAME, AND POLYAMIDE-IMIDE FILM COMPRISING SAME LG Chem, Ltd. (KR) 2021-11-17 EP disclosed
US-9914098-B2 Flux enhancing agent for improving composite polyamide reverse osmosis membrane performance BL TECHNOLOGIES, INC. 2018-03-13 US disclosed
EP-3006610-B1 ORGANIC RESIN NON-CRIMPED STAPLE FIBER TEIJIN LTD (JP) 2017-07-19 EP disclosed
US-20160193572-A1 Novel Flux Enhancing Agent for Improving Composite Polyamide Reverse Osmosis Membrane Performance BL TECHNOLOGIES, INC. 2016-07-07 US disclosed
US-20160177476-A1 ORGANIC RESIN NON-CRIMPED STAPLE FIBER TEIJIN LIMITED (JP) 2016-06-23 US disclosed
US-9346023-B2 Flux enhancing agent for improving composite polyamide reverse osmosis membrane performance GENERAL ELECTRIC COMPANY (US) 2016-05-24 US disclosed
US-9314743-B2 Residential reverse osmosis system PENTAIR RESIDENTIAL FILTRATION, LLC (US) 2016-04-19 US disclosed
EP-3006610-A1 ORGANIC RESIN NON-CRIMPED STAPLE FIBER Teijin Limited (JP) 2016-04-13 EP disclosed
CN-1049799-A HIGH FLUX SEMIPERMEABLE MEMBRANES ALLIED SIGNAL INC (US) 1991-03-13 CN disclosed
US-4983291-A Reverse osmosis, desalination, coating support with polyamine, reacting with polyacyl halide, polysulfonyl halide or polyisocyanate ALLIED-SIGNAL INC. (US) 1991-01-08 US disclosed
WO-1990010494-A1 CHLORINE-RESISTANT SEMIPERMEABLE MEMBRANES ALLIED-SIGNAL INC. (US) 1990-09-20 WO disclosed
US-4950404-A REVERSE OSMOSIS; WATER DESLINATION ALLIED-SIGNAL INC. (US) 1990-08-21 US disclosed
US-4830885-A POLYAMIDES ALLIED-SIGNAL INC. (US) 1989-05-16 US disclosed
EP-0069157-A1 Alternating copolyestercarbonate resins THE DOW CHEMICAL COMPANY (US) 1983-01-12 EP disclosed
US-4278787-A RADIATION TRANSPARENT, TOUGHNESS, HEAT RESISTANCE THE DOW CHEMICAL COMPANY (US) 1981-07-14 US disclosed
US-4221895-A POLYESTER, POLYSULFONATE, OR POLYSULFINATE THE DOW CHEMICAL COMPANY (US) 1980-09-09 US disclosed