SCHEMBL3356289

SCHEMBL3356289

O=C(O)c1cccc(C(=O)I)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.58
CA1 P00915 1/20 0.58
CA2 P00918 1/20 0.58
CA6 P23280 1/20 0.58
CA9 Q16790 1/20 0.58
KMO O15229 1/20 0.54
CYP1A2 P05177 1/20 0.54
CYP2C9 P11712 1/20 0.54
HPGD P15428 1/20 0.54
HSD17B10 Q99714 1/20 0.54
L3MBTL1 Q9Y468 2/20 0.53
PKM P14618 1/20 0.53
DAO P14920 1/20 0.52
TSHR P16473 1/20 0.52
NAPRT Q6XQN6 1/20 0.52
UNG P13051 1/20 0.52
RXRA P19793 1/20 0.52
RXRB P28702 1/20 0.52
ATM Q13315 1/20 0.50
TDP1 Q9NUW8 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL813336 0.90 L3MBTL1 (0.52) CA12CA1CA2CA6CA9
Isophthalic Acid SCHEMBL20500514 0.87 CA12 (0.71) CA12CA1CA2CA6CA9
Isophthalic Acid SCHEMBL22462 0.87 CA12 (0.71) CA12CA1CA2CA6CA9
Isophthalic Acid SCHEMBL147366 0.87 CA12 (0.71) CA12CA1CA2CA6CA9
Isophthalic Acid SCHEMBL2512374 0.87 CA12 (0.71) CA12CA1CA2CA6CA9
Isophthalic Acid SCHEMBL28756611 0.87 CA12 (0.71) CA12CA1CA2CA6CA9
Isophthalic Acid SCHEMBL28462260 0.87 CA12 (0.71) CA12CA1CA2CA6CA9
Isophthalic Acid SCHEMBL25202015 0.85 CA12 (0.68) CA12CA1CA2CA6CA9
Isophthalic Acid SCHEMBL10897679 0.85 CA12 (0.68) CA12CA1CA2CA6CA9
Isophthalic Acid SCHEMBL10696844 0.85 CA12 (0.68) CA12CA1CA2CA6CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2157151-B1 ELECTROCHROMIC MATERIALS AND ELECTROCHROMIC DEVICES USING THE SAME SAMSUNG ELECTRONICS CO LTD (KR) 2017-04-12 EP disclosed
US-9228124-B2 Electrochromic materials and electrochromic devices using the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-01-05 US disclosed
US-20120307339-A1 ELECTROCHROMIC MATERIALS AND ELECTROCHROMIC DEVICES USING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2012-12-06 US disclosed
US-8274213-B2 Electrochromic materials and electrochromic devices using the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2012-09-25 US disclosed
EP-2157151-A1 Electrochromic materials and electrochromic devices using the same Samsung Electronics Co., Ltd. (KR) 2010-02-24 EP disclosed
US-20100039025-A1 ELECTROCHROMIC MATERIALS AND ELECTROCHROMIC DEVICES USING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2010-02-18 US disclosed
US-20080161306-A1 Pyrrole Derivatives as Dna Gyrase and Topoisomerase Inhibitors ASTRAZENECA AB (SE) 2008-07-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120307339-A1 ELECTROCHROMIC MATERIALS AND ELECTROCHROMIC DEVICES USING THE SAME FHIT, RPS10, ESYT2 CA12 1390/4885CA1 2111/4885CA2 2655/4885
US-20100039025-A1 ELECTROCHROMIC MATERIALS AND ELECTROCHROMIC DEVICES USING THE SAME FHIT, RPS10, ESYT2 CA12 1390/4885CA1 2111/4885CA2 2655/4885
US-20080161306-A1 Pyrrole Derivatives as Dna Gyrase and Topoisomerase Inhibitors TOP1, TOP2A, TOP2B CA12 3629/4885CA1 3325/4885CA2 1959/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.