Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL126792 | 1.00 | ALDH1A1 (0.32) | ALDH1A1TP53TSHRHIF1AHSD17B10 | |
| SCHEMBL827285 | 1.00 | ALDH1A1 (0.32) | ALDH1A1TP53TSHRHIF1AHSD17B10 | |
| Ethylene Glycol Diformate SCHEMBL827902 | 0.89 | — | — | |
| SCHEMBL4396264 | 0.86 | ALDH1A1 (0.41) | ALDH1A1TSHR | |
| SCHEMBL22041029 | 0.86 | MEN1 (0.58) | ALDH1A1TP53TSHRHIF1AHSD17B10 | |
| SCHEMBL24292276 | 0.86 | CA2 (0.38) | — | |
| SCHEMBL1010288 | 0.86 | — | — | |
| SCHEMBL3081170 | 0.86 | MEN1 (0.58) | ALDH1A1TP53TSHRHIF1AHSD17B10 | |
| SCHEMBL7571486 | 0.86 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL4397692 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7968668-B2 | Diisocyanate terminated macromer and formulation thereof for use as an internal adhesive or sealant | ETHICON INC. (US) | 2011-06-28 | — | — | US | disclosed |
| US-7728097-B2 | Method of making a diisocyanate terminated macromer | ETHICON, INC. (US) | 2010-06-01 | — | — | US | disclosed |
| US-20070167617-A1 | Method of making a diisocyanate terminated macromer | ETHICON, INC. | 2007-07-19 | — | — | US | disclosed |