Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13294049 | 0.89 | RAB9A (0.55) | RAB9ANPC1CASP1MAPTALDH1A1 | |
| SCHEMBL813494 | 0.86 | NPC1 (0.55) | RAB9ANPC1CASP1MAPTALDH1A1 | |
| SCHEMBL13294050 | 0.86 | HPGD (0.63) | RAB9ANPC1CASP1MAPTALDH1A1 | |
| SCHEMBL14134604 | 0.83 | HPGD (0.57) | RAB9ANPC1MAPTALDH1A1MEN1 | |
| SCHEMBL2354864 | 0.80 | RAB9A (0.57) | RAB9ANPC1CASP1MAPTALDH1A1 | |
| SCHEMBL15714980 | 0.78 | MAPT (0.72) | RAB9ANPC1MAPTALDH1A1MEN1 | |
| SCHEMBL14075726 | 0.78 | HPGD (0.50) | RAB9AMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL14442109 | 0.76 | HPGD (0.64) | RAB9ANPC1CASP1MAPTMEN1 | |
| SCHEMBL10943133 | 0.76 | RAB9A (0.86) | RAB9ANPC1CASP1MAPTALDH1A1 | |
| SCHEMBL13292517 | 0.75 | TDP1 (0.54) | RAB9ANPC1MAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7968668-B2 | Diisocyanate terminated macromer and formulation thereof for use as an internal adhesive or sealant | ETHICON INC. (US) | 2011-06-28 | — | — | US | disclosed |
| US-20070167617-A1 | Method of making a diisocyanate terminated macromer | ETHICON, INC. | 2007-07-19 | — | — | US | disclosed |