Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDAH1 | O94760 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PGD | P52209 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2329737 | 0.83 | ALDH1A1 (0.43) | MEN1KMT2AALDH1A1NOS3NOS1 | |
| SCHEMBL5830956 | 0.79 | KMT2A (0.34) | DDAH1MEN1KMT2AALDH1A1CA2 | |
| SCHEMBL21877045 | 0.79 | KMT2A (0.34) | DDAH1MEN1KMT2AALDH1A1CA2 | |
| SCHEMBL28544923 | 0.78 | MEN1 (0.39) | DDAH1MEN1KMT2AALDH1A1CA2 | |
| SCHEMBL27213086 | 0.78 | ALDH1A1 (0.32) | DDAH1ALDH1A1CA2KDM4EPOLB | |
| SCHEMBL29257033 | 0.78 | ALDH1A1 (0.32) | DDAH1ALDH1A1CA2KDM4EPOLB | |
| Bicarbonate SCHEMBL27364872 | 0.77 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1CA2TSHR | |
| Bicarbonate SCHEMBL9083427 | 0.77 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1CA2TSHR | |
| SCHEMBL5830472 | 0.76 | SMN1; SMN2 (0.34) | DDAH1ALDH1A1CA2KDM4E | |
| SCHEMBL7653761 | 0.76 | SMN1; SMN2 (0.34) | DDAH1ALDH1A1CA2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2276356-A1 | WARMING SENSATE COMPOSITION | Firmenich S.A. (CH) | 2011-01-26 | — | — | EP | claimed |
| JP-4608499-B2 | — | — | 2011-01-12 | — | — | JP | claimed |
| WO-2009127992-A1 | WARMING SENSATE COMPOSITION | FIRMENICH SA (CH) | 2009-10-22 | — | — | WO | claimed |
| JP-2007516316-A | — | — | 2007-06-21 | — | — | JP | claimed |
| EP-1682641-A1 | FLAVOR INGREDIENTS FOR COOLING PREPARATIONS | FIRMENICH SA (CH) | 2006-07-26 | — | — | EP | claimed |
| WO-2005042680-A1 | FLAVOR INGREDIENTS FOR COOLING PREPARATIONS | FIRMENICH SA (CH) | 2005-05-12 | — | — | WO | claimed |