Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7653761 | 1.00 | SMN1; SMN2 (0.34) | SMN1; SMN2CYP4F2CYP4A11ALDH1A1DDAH1 | |
| SCHEMBL3426355 | 0.94 | SMN1; SMN2 (0.37) | SMN1; SMN2CYP4F2CYP4A11ALDH1A1DDAH1 | |
| SCHEMBL27213086 | 0.86 | ALDH1A1 (0.32) | ALDH1A1DDAH1KDM4ECA2 | |
| SCHEMBL29257033 | 0.86 | ALDH1A1 (0.32) | ALDH1A1DDAH1KDM4ECA2 | |
| SCHEMBL7648423 | 0.85 | PPARG (0.40) | DDAH1ABCB11CYP3A4ADRA2BOPRD1 | |
| SCHEMBL12171733 | 0.85 | ALDH1A1 (0.33) | ALDH1A1DDAH1KDM4ECA2 | |
| SCHEMBL28789913 | 0.85 | MEN1 (0.42) | SMN1; SMN2CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL16246663 | 0.84 | ALDH1A1 (0.43) | SMN1; SMN2CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL4782571 | 0.83 | TSHR (0.42) | SMN1; SMN2CYP4F2CYP4A11ALDH1A1KDM4E | |
| SCHEMBL1904784 | 0.83 | CPB2 (0.40) | SMN1; SMN2CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7041721-B2 | Highly neutralized polymer golf ball compositions including oxa acids and methods of making same | ACUSHNET COMPANY (US) | 2006-05-09 | — | — | US | claimed |
| EP-0910362-B1 | OXA ACIDS AND RELATED COMPOUNDS FOR TREATING SKIN CONDITIONS | AVON PROD INC (US) | 2004-10-27 | — | — | EP | claimed |
| US-20030225197-A1 | Highly neutralized polymer golf ball compositions including oxa acids and methods of making same | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT | 2003-12-04 | — | — | US | claimed |
| US-6534543-B2 | Topical compositions with carboxy acid/ester, amide, or thioester/thioacid groups, with one or more of ether, amine, or sulfide groups; for example 3,6-dioxaheptanioic acid; peeling skin, softening hair | AVON PRODUCTS, INC. | 2003-03-18 | — | — | US | claimed |
| US-20020040056-A1 | Oxa acids and related compounds for treating skin conditions | AVON PRODUCTS, INC. | 2002-04-04 | — | — | US | claimed |
| JP-2000511900-A | — | — | 2000-09-12 | — | — | JP | claimed |
| US-6069169-A | OXA acids and related compounds for treating skin conditions | AVON PRODUCTS, INC. (US) | 2000-05-30 | — | — | US | claimed |
| EP-0910362-A4 | OXA ACIDS AND RELATED COMPOUNDS FOR TREATING SKIN CONDITIONS | AVON PROD INC (US) | 1999-12-22 | — | — | EP | claimed |
| EP-0910362-A1 | OXA ACIDS AND RELATED COMPOUNDS FOR TREATING SKIN CONDITIONS | AVON PRODUCTS, INC. (US) | 1999-04-28 | — | — | EP | claimed |
| US-5847003-A | Oxa acids and related compounds for treating skin conditions | AVON PRODUCTS, INC. (US) | 1998-12-08 | — | — | US | claimed |
| WO-1997046231-A1 | OXA ACIDS AND RELATED COMPOUNDS FOR TREATING SKIN CONDITIONS | AVON PRODUCTS, INC. (US) | 1997-12-11 | — | — | WO | claimed |
| US-7041721-B2 | Highly neutralized polymer golf ball compositions including oxa acids and methods of making same | ACUSHNET COMPANY (US) | 2006-05-09 | — | — | US | disclosed |
| EP-0910362-B1 | OXA ACIDS AND RELATED COMPOUNDS FOR TREATING SKIN CONDITIONS | AVON PROD INC (US) | 2004-10-27 | — | — | EP | disclosed |
| US-20030225197-A1 | Highly neutralized polymer golf ball compositions including oxa acids and methods of making same | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT | 2003-12-04 | — | — | US | disclosed |
| US-6534543-B2 | Topical compositions with carboxy acid/ester, amide, or thioester/thioacid groups, with one or more of ether, amine, or sulfide groups; for example 3,6-dioxaheptanioic acid; peeling skin, softening hair | AVON PRODUCTS, INC. | 2003-03-18 | — | — | US | disclosed |
| US-6333356-B1 | TOPICAL COMPOUNDS FOR SKIN DISORDERS | AVON PRODUCTS, INC. | 2001-12-25 | — | — | US | disclosed |
| US-6071962-A | IN TOPICAL APPLICATIONS TO TREAT VARIOUS SKIN CONDITIONS ATTRIBUTED TO, ACCOMPANIED BY OR EXACERBATED BY ABNORMAL DESQUAMATION INCLUDING DRY SKIN, ICHTHYOSIS, PALMAR AND PLANTAR HYPERKERATOSES, DANDRUFF, LICHEN SIMPLEX CHRONICUS | AVON PRODUCTS, INC. (US) | 2000-06-06 | — | — | US | disclosed |
| US-6069169-A | OXA acids and related compounds for treating skin conditions | AVON PRODUCTS, INC. (US) | 2000-05-30 | — | — | US | disclosed |
| EP-0910362-A4 | OXA ACIDS AND RELATED COMPOUNDS FOR TREATING SKIN CONDITIONS | AVON PROD INC (US) | 1999-12-22 | — | — | EP | disclosed |
| EP-0910362-A1 | OXA ACIDS AND RELATED COMPOUNDS FOR TREATING SKIN CONDITIONS | AVON PRODUCTS, INC. (US) | 1999-04-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020040056-A1 | Oxa acids and related compounds for treating skin conditions | OXGR1, OXA1L, CXCR1 | SMN1; SMN2 2465/4885CYP4F2 1910/4885CYP4A11 364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.