SCHEMBL8134147

SCHEMBL8134147

Cc1cc(-c2c(S(C)(=O)=O)ccc(C(=O)C3C(=O)CC4CC4C3=O)c2C)on1

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
ALDH1A1 P00352 2/20 0.31
MAPT P10636 1/20 0.31
HSD17B10 Q99714 1/20 0.31
KDM4E B2RXH2 1/20 0.31
USP2 O75604 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8135848 0.83 MEN1 (0.32) MEN1KMT2AALDH1A1MAPTKDM4E
SCHEMBL8135835 0.83 PIK3CD (0.35) MEN1KMT2AALDH1A1MAPTKDM4E
SCHEMBL8127129 0.83 MEN1 (0.33) MEN1KMT2AALDH1A1MAPTHSD17B10
SCHEMBL8136634 0.80 MEN1 (0.31) MEN1KMT2A
SCHEMBL8136516 0.79 TP53 (0.31) MEN1KMT2A
SCHEMBL8128601 0.79 GPR119 (0.31) MEN1KMT2AMAPT
SCHEMBL6587396 0.76 KDM4E (0.40) MEN1KMT2AALDH1A1MAPTKDM4E
SCHEMBL6587430 0.75 ALDH1A1 (0.50) MEN1KMT2AALDH1A1MAPTKDM4E
SCHEMBL8309940 0.74 CSF1R (0.31) MEN1KMT2AALDH1A1MAPTHSD17B10
SCHEMBL8138245 0.74 CSF1R (0.37) ALDH1A1MAPTKDM4EUSP2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6100421-A METHYL 3-FORMYL-4-METHANESULFONYL-2-METHYLBENZOATE, USEFUL AS A STARTING MATERIAL FOR HERBICIDE MANUFACTURE NIPPON SODA CO., LTD. (JP) 2000-08-08 US disclosed
EP-0894792-A1 HETEROCYCLE-SUBSTITUTED BENZENE DERIVATIVES AND HERBICIDES NIPPON SODA CO., LTD. (JP) 1999-02-03 EP disclosed