Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | TACR3 | P29371 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8133350 | 0.84 | ADORA2A (0.39) | HTTKDM4EHSD17B10TP53GAA | |
| SCHEMBL28854593 | 0.82 | ALDH1A1 (0.38) | KDM4EALDH1A1GRM2ADORA2AADORA1 | |
| SCHEMBL30069495 | 0.77 | HTT (0.34) | HTTKDM4EHSD17B10TP53GAA | |
| SCHEMBL164293 | 0.77 | HTT (0.34) | HTTKDM4EHSD17B10TP53GAA | |
| SCHEMBL8208035 | 0.77 | KDM4E (0.41) | HTTKDM4EHSD17B10TP53GAA | |
| SCHEMBL1278314 | 0.76 | PDE10A (0.57) | HTTKDM4EHSD17B10TP53GAA | |
| SCHEMBL6076632 | 0.76 | HTT (0.31) | HTTKDM4EHSD17B10TP53GAA | |
| SCHEMBL6076636 | 0.76 | HTT (0.31) | HTTKDM4EHSD17B10TP53GAA | |
| SCHEMBL2819557 | 0.74 | HTT (0.35) | HTTKDM4EHSD17B10TP53GAA | |
| SCHEMBL28852217 | 0.73 | PARP1 (0.36) | KDM4EALDH1A1GRM2ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0669321-B1 | Use of 4-acyloxyquinoline derivatives as insecticides or acaricides | MEIJI SEIKA CO (JP) | 2000-09-27 | — | — | EP | claimed |