Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PREP | P48147 | 2/20 | 0.34 |
| ▸ | CELA1 | Q9UNI1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29370903 | 0.80 | KDM4E (0.47) | KDM4EHTTHSD17B10GAAMAPT | |
| SCHEMBL9627562 | 0.77 | PDE4A (0.41) | KDM4EHTTHSD17B10GAAMAPT | |
| SCHEMBL8134178 | 0.77 | HTT (0.39) | KDM4EHTTHSD17B10GAAMAPT | |
| SCHEMBL9627915 | 0.74 | PDE4A (0.41) | KDM4EHTTHSD17B10GAAMAPT | |
| SCHEMBL1994318 | 0.74 | KMT2A (0.49) | KDM4EHTTHSD17B10GAAMAPT | |
| SCHEMBL13666895 | 0.73 | KDM4E (0.62) | KDM4EHTTHSD17B10GAAMAPT | |
| SCHEMBL14181682 | 0.72 | KDM4E (0.61) | KDM4EHTTHSD17B10GAAMAPT | |
| SCHEMBL9629235 | 0.72 | KDM4E (0.41) | KDM4EHTTHSD17B10GAAMAPT | |
| SCHEMBL9629349 | 0.71 | ALDH1A1 (0.40) | KDM4EHTTHSD17B10GAAMAPT | |
| SCHEMBL9627706 | 0.71 | KDM4E (0.45) | KDM4EHTTHSD17B10GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6045590-A | REPLACING 2-METHYL-1-NAPHTHOL WITH A MOLAR EQUIVALENT OF A 1-(ALKOXYCARBONYLOXY OR ALKYLCARBONYLOXY),2-METHYL-NAPHTHYLENE OR 2-METHYL,4-((HYDROXY)(ALKOXY)ALKOXY)-NAPHTH-1-OL; STORAGE STABLE HAIR DYES PRODUCE SAME COLOR | BRISTOL-MYERS SQUIBB CO. (US) | 2000-04-04 | — | — | US | disclosed |
| US-5672180-A | USED IN OXIDATIVE HAIR DYE SYSTEMS | CLAIROL INCORPORATED (US) | 1997-09-30 | — | — | US | disclosed |
| US-5529583-A | HAIR DYE | CLAIROL INCORPORATED (US) | 1996-06-25 | — | — | US | disclosed |