Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.32 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MAT2A | P31153 | 3/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8940911 | 0.83 | RAB9A (0.31) | RAB9ASMN1; SMN2LMNAALDH1A1CYP1A2 | |
| SCHEMBL8941039 | 0.82 | PDE4B (0.32) | RAB9ASMN1; SMN2LMNAALDH1A1CYP1A2 | |
| SCHEMBL8130838 | 0.81 | TNF (0.32) | TNFNOD1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL8131410 | 0.76 | MEN1 (0.37) | LMNAALDH1A1POLB | |
| SCHEMBL6721329 | 0.76 | LMNA (0.34) | RAB9ASMN1; SMN2LMNAALDH1A1CYP1A2 | |
| SCHEMBL8895824 | 0.75 | SMN1; SMN2 (0.33) | RAB9ASMN1; SMN2LMNAALDH1A1CYP1A2 | |
| SCHEMBL8455943 | 0.75 | RAB9A (0.32) | RAB9ASMN1; SMN2LMNAALDH1A1CYP1A2 | |
| SCHEMBL8123433 | 0.75 | RAB9A (0.33) | RAB9ASMN1; SMN2LMNAALDH1A1CYP1A2 | |
| SCHEMBL8871769 | 0.72 | KDM4E (0.31) | RAB9ASMN1; SMN2LMNA | |
| SCHEMBL8871773 | 0.72 | KDM4E (0.31) | RAB9ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6159904-A | Pyrazole derivatives | IDEMITSU KOSAN CO., LTD. (JP) | 2000-12-12 | — | — | US | disclosed |
| EP-0970956-A1 | PYRAZOLE DERIVATIVES | IDEMITSU KOSAN COMPANY LIMITED (JP) | 2000-01-12 | — | — | EP | disclosed |