Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 1/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.70 |
| ▸ | HPGD | P15428 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | ATM | Q13315 | 1/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.51 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27517425 | 0.88 | NPC1 (0.55) | MEN1CYP1A2MAPTCYP2C9HPGD | |
| SCHEMBL10966645 | 0.85 | MAPT (0.51) | MEN1CYP1A2MAPTCYP2C9HPGD | |
| SCHEMBL13996081 | 0.85 | ALDH1A1 (0.51) | MEN1CYP1A2MAPTCYP2C9HPGD | |
| SCHEMBL8854898 | 0.84 | MEN1 (0.51) | MEN1CYP1A2MAPTCYP2C9HPGD | |
| SCHEMBL7913550 | 0.82 | LMNA (0.73) | MEN1CYP1A2MAPTCYP2C9HPGD | |
| SCHEMBL8143320 | 0.80 | LMNA (0.61) | MEN1CYP1A2MAPTCYP2C9HPGD | |
| SCHEMBL11013258 | 0.80 | ADORA2A (0.59) | MEN1CYP1A2MAPTCYP2C9HPGD | |
| SCHEMBL3304516 | 0.80 | MEN1 (0.48) | MEN1CYP1A2MAPTCYP2C9HPGD | |
| SCHEMBL14988002 | 0.80 | MAPK1 (0.88) | MEN1CYP1A2MAPTCYP2C9HPGD | |
| SCHEMBL10965468 | 0.80 | ALDH1A1 (0.59) | MEN1CYP1A2MAPTCYP2C9HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009005677-A2 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2009-01-08 | — | — | WO | disclosed |