SCHEMBL8134580

SCHEMBL8134580

COc1cccc(P(Cl)Cl)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.50
CYP3A4 P08684 2/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA7 P43166 1/20 0.48
CA9 Q16790 1/20 0.48
ALDH1A1 P00352 1/20 0.48
CES2 O00748 1/20 0.44
CES1 P23141 1/20 0.44
ENPP2 Q13822 1/20 0.44
CHRM5 P08912 1/20 0.42
CA4 P22748 1/20 0.42
IDO1 P14902 2/20 0.41
AGXT P21549 2/20 0.41
CYP1A1 P04798 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2E1 P05181 1/20 0.41
CYP2C8 P10632 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2A6 P11509 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2154398 0.87 ACHE (0.50) ACHECYP3A4CA1CA2CA7
SCHEMBL29635198 0.82 ACHE (0.54) ACHECYP3A4CA1CA2CA7
SCHEMBL197286 0.82 ACHE (0.54) ACHECYP3A4CA1CA2CA7
SCHEMBL2155242 0.82 CA4 (0.48) ACHECYP3A4CA1CA2CA7
SCHEMBL31189339 0.80 ACHE (0.52) ACHECYP3A4CA1CA2CA7
SCHEMBL2155304 0.80 ACHE (0.52) ACHECYP3A4CA1CA2CA7
Hydrochloric Acid SCHEMBL5427158 0.80 ACHE (0.52) ACHECYP3A4CA1CA2CA7
SCHEMBL9420847 0.80 ACHE (0.52) ACHECYP3A4CA1CA2CA7
Phosphine SCHEMBL6466867 0.80 ACHE (0.52) ACHECYP3A4CA1CA2CA7
SCHEMBL5713343 0.80 ACHE (0.52) ACHECYP3A4CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2000002890-A1 HYDROFORMYLATION PROCESS NESTE CHEMICALS OY (FI) 2000-01-20 WO disclosed