SCHEMBL9420847

SCHEMBL9420847

COc1cccc(P(C)C)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.52
CYP3A4 P08684 2/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
ALDH1A1 P00352 1/20 0.50
TAAR1 Q96RJ0 1/20 0.47
CES2 O00748 1/20 0.45
CES1 P23141 1/20 0.45
ENPP2 Q13822 1/20 0.45
CA4 P22748 1/20 0.44
CHRM5 P08912 1/20 0.44
CYP1A2 P05177 2/20 0.42
CYP2A6 P11509 2/20 0.42
IDO1 P14902 2/20 0.42
AGXT P21549 2/20 0.42
CYP1A1 P04798 1/20 0.42
CYP2E1 P05181 1/20 0.42
CYP2C8 P10632 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL197286 0.84 ACHE (0.54) ACHECYP3A4CA1CA2CA7
SCHEMBL29635198 0.84 ACHE (0.54) ACHECYP3A4CA1CA2CA7
SCHEMBL31189339 0.82 ACHE (0.52) ACHECYP3A4CA1CA2CA7
SCHEMBL5713343 0.82 ACHE (0.52) ACHECYP3A4CA1CA2CA7
Hydrochloric Acid SCHEMBL5427158 0.82 ACHE (0.52) ACHECYP3A4CA1CA2CA7
Phosphine SCHEMBL6466867 0.82 ACHE (0.52) ACHECYP3A4CA1CA2CA7
SCHEMBL2155304 0.82 ACHE (0.52) ACHECYP3A4CA1CA2CA7
SCHEMBL2154398 0.80 ACHE (0.50) ACHECYP3A4CA1CA2CA7
SCHEMBL8134580 0.80 ACHE (0.50) ACHECYP3A4CA1CA2CA7
SCHEMBL8030637 0.78 CA4 (0.52) ACHECYP3A4CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0144936-B2 Production of carboxylic acids from alcohols UNION CARBIDE CORP (US) 1994-03-09 EP disclosed
EP-0144936-B1 PRODUCTION OF CARBOXYLIC ACIDS FROM ALCOHOLS UNION CARBIDE CORPORATION (US) 1987-06-24 EP disclosed
EP-0068499-B1 CATALYST AND PROCESS FOR THE CONVERSION OF METHANOL TO ACETALDEHYDE UNION CARBIDE CORPORATION (US) 1985-04-24 EP disclosed
US-4511741-A COBALT AND RHODIUM CATALYST, LITHIUM HALIDE PROMOTER UNION CARBIDE CORPORATION (US) 1985-04-16 US disclosed
EP-0029086-B1 IMPROVED PROCESS FOR THE PRODUCTION OF ETHANOL AND CATALYST THEREOF UNION CARBIDE CORPORATION (US) 1984-09-12 EP disclosed
EP-0034374-B1 SELECTIVE HOMOLOGATION OF ACETALS OR ETHERS TO MONOHYDRIC OR POLYHYDRIC ALCOHOLS UNION CARBIDE CORPORATION (US) 1983-08-03 EP disclosed
US-4374752-A COBALT, HALIDE, AN TRIVALENT AND PHOSPHORUS COMPOUND IN AN INERT DILUENT UNION CARBIDE CORPORATION (US) 1983-02-22 US disclosed
EP-0068499-A1 Catalyst and process for the conversion of methanol to acetaldehyde UNION CARBIDE CORPORATION (US) 1983-01-05 EP disclosed
EP-0034374-A1 Selective homologation of acetals or ethers to monohydric or polyhydric alcohols UNION CARBIDE CORPORATION (US) 1981-08-26 EP disclosed
EP-0029086-A1 Improved process for the production of ethanol and catalyst thereof UNION CARBIDE CORPORATION (US) 1981-05-27 EP disclosed
US-4253987-A PHOSPHINE LIGAND-IODINE PROMOTED COBALT OR RUTHENIUM CATALYST UNION CARBIDE CORPORATION (US) 1981-03-03 US disclosed
US-4233466-A CATALYZED BY A PHOSPHINE-IODINE PROMOTED COBALT-RUTHENIUM CATALYST UNION CARBIDE CORPORATION (US) 1980-11-11 US disclosed