Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.79 |
| ▸ | RECQL | P46063 | 1/20 | 0.79 |
| ▸ | PKM | P14618 | 2/20 | 0.77 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.63 |
| ▸ | MEN1 | O00255 | 5/20 | 0.63 |
| ▸ | MAPT | P10636 | 4/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.60 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.60 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL813368 | 0.93 | HPGD (0.70) | HPGDRECQLPKMMAPK1HSD17B10 | |
| SCHEMBL10666168 | 0.91 | HPGD (0.67) | HPGDRECQLPKMMAPK1HSD17B10 | |
| Hydrochloric Acid SCHEMBL11161378 | 0.90 | HPGD (0.80) | HPGDRECQLPKMMAPK1HSD17B10 | |
| SCHEMBL12050126 | 0.89 | HPGD (0.65) | HPGDRECQLPKMMAPK1HSD17B10 | |
| SCHEMBL11163640 | 0.89 | HPGD (0.78) | HPGDRECQLPKMMAPK1HSD17B10 | |
| SCHEMBL13294050 | 0.88 | HPGD (0.63) | HPGDRECQLPKMMAPK1HSD17B10 | |
| SCHEMBL7473283 | 0.87 | HPGD (0.67) | HPGDRECQLPKMMAPK1HSD17B10 | |
| SCHEMBL4289783 | 0.87 | HPGD (0.71) | HPGDRECQLPKMMAPK1HSD17B10 | |
| SCHEMBL14442109 | 0.85 | HPGD (0.64) | HPGDRECQLPKMMAPK1HSD17B10 | |
| SCHEMBL3364980 | 0.85 | HPGD (0.68) | HPGDRECQLPKMMAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7968668-B2 | Diisocyanate terminated macromer and formulation thereof for use as an internal adhesive or sealant | ETHICON INC. (US) | 2011-06-28 | — | — | US | disclosed |