Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.71 |
| ▸ | TSHR | P16473 | 1/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA5A | P35218 | 1/20 | 0.49 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | ILK | Q13418 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL334808 | 0.84 | ALDH1A1 (1.00) | ALDH1A1CYP3A4TSHRTDP1SMN1; SMN2 | |
| SCHEMBL5049722 | 0.83 | ALDH1A1 (0.86) | ALDH1A1CYP3A4TSHRTDP1SMN1; SMN2 | |
| Nitrogen SCHEMBL28651597 | 0.82 | ALDH1A1 (0.94) | ALDH1A1CYP3A4TSHRTDP1SMN1; SMN2 | |
| Sulfuric Acid SCHEMBL28206216 | 0.78 | ALDH1A1 (0.86) | ALDH1A1CYP3A4TSHRTDP1SMN1; SMN2 | |
| SCHEMBL2172967 | 0.78 | SMN1; SMN2 (0.75) | ALDH1A1CYP3A4TSHRTDP1SMN1; SMN2 | |
| SCHEMBL29992706 | 0.77 | ALDH1A1 (1.00) | ALDH1A1CYP3A4TSHRTDP1SMN1; SMN2 | |
| SCHEMBL94937 | 0.77 | ALDH1A1 (1.00) | ALDH1A1CYP3A4TSHRTDP1SMN1; SMN2 | |
| SCHEMBL11058789 | 0.76 | HSD17B10 (0.58) | ALDH1A1CYP3A4TSHRTDP1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11081862 | 0.76 | ALDH1A1 (0.96) | ALDH1A1CYP3A4TSHRTDP1SMN1; SMN2 | |
| Bromide SCHEMBL11833484 | 0.76 | ALDH1A1 (0.96) | ALDH1A1CYP3A4TSHRTDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1049682-A1 | OXAZOLIDINONE COMBINATORIAL LIBRARIES, COMPOSITIONS AND METHODS OF PREPARATION | Versicor, Inc. (US) | 2000-11-08 | — | — | EP | disclosed |
| WO-1999037630-A1 | OXAZOLIDINONE COMBINATORIAL LIBRARIES, COMPOSITIONS AND METHODS OF PREPARATION | VERSICOR, INC. (US) | 1999-07-29 | — | — | WO | disclosed |