Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.75 |
| ▸ | TSHR | P16473 | 1/20 | 0.75 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.75 |
| ▸ | HTT | P42858 | 1/20 | 0.75 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA5A | P35218 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31219335 | 0.87 | ALDH1A1 (0.77) | SMN1; SMN2ALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL334808 | 0.87 | ALDH1A1 (1.00) | SMN1; SMN2ALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL3244369 | 0.87 | SMN1; SMN2 (1.00) | SMN1; SMN2ALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL84324 | 0.87 | SMN1; SMN2 (0.77) | SMN1; SMN2ALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL482233 | 0.87 | ALDH1A1 (0.77) | SMN1; SMN2ALDH1A1CYP3A4TSHRTDP1 | |
| Nitrogen SCHEMBL28651597 | 0.84 | ALDH1A1 (0.94) | SMN1; SMN2ALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL5049722 | 0.83 | ALDH1A1 (0.86) | SMN1; SMN2ALDH1A1CYP3A4TSHRTDP1 | |
| Sulfuric Acid SCHEMBL28206216 | 0.80 | ALDH1A1 (0.86) | SMN1; SMN2ALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL8136089 | 0.78 | ALDH1A1 (0.71) | SMN1; SMN2ALDH1A1CYP3A4TSHRTDP1 | |
| Hydrochlorthiazide SCHEMBL9107766 | 0.75 | ALDH1A1 (0.75) | SMN1; SMN2ALDH1A1CYP3A4TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346956-A1 | ACTIVATORS FOR TWO PART CYANOACRYLATE ADHESIVES | Loctite (R & D) Limited (IE) | 2011-07-27 | — | — | EP | disclosed |
| WO-2010046412-A1 | ACTIVATORS FOR TWO PART CYANOACRYLATE ADHESIVES | LOCTITE (R & D) LIMITED (IE) | 2010-04-29 | — | — | WO | disclosed |