Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | VDR | P11473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8137079 | 0.83 | ALDH1A1 (0.48) | MAPK1KDM4EALDH1A1HSD17B10POLB | |
| SCHEMBL8140152 | 0.77 | ALDH1A1 (0.49) | MAPK1KDM4EALDH1A1HSD17B10POLB | |
| SCHEMBL8133556 | 0.76 | MAPK1 (0.46) | MAPK1KDM4EALDH1A1HSD17B10POLB | |
| SCHEMBL5102962 | 0.76 | MAPK1 (0.46) | MAPK1KDM4EALDH1A1HSD17B10POLB | |
| SCHEMBL5102959 | 0.76 | MAPK1 (0.46) | MAPK1KDM4EALDH1A1HSD17B10POLB | |
| SCHEMBL6611465 | 0.75 | HDAC1 (0.38) | — | |
| SCHEMBL13592435 | 0.75 | GRIA1 (0.34) | KDM4EALDH1A1CYP1A2MAOAKCNH2 | |
| SCHEMBL14287214 | 0.74 | LMNA (0.50) | MAPK1KDM4EALDH1A1HSD17B10LMNA | |
| Hydrochloric Acid SCHEMBL4377355 | 0.74 | MEN1 (0.41) | POLBCYP1A2CYP3A4MAOACYP2C9 | |
| Hydrochloric Acid SCHEMBL6613546 | 0.73 | ALDH1A1 (0.42) | MAPK1KDM4EALDH1A1CYP1A2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0781285-B1 | FUSED INDOLE AND QUINOXALINE DERIVATIVES, THEIR PREPARATION AND USE AS GLUTAMATE ANTAGONISTS | NEUROSEARCH AS (DK) | 2000-01-12 | — | — | EP | disclosed |
| US-5801174-A | CEREBROVASCULAR DISORDERS | NEUROSEARCH A/S (DK) | 1998-09-01 | — | — | US | disclosed |