Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8126965 | 0.80 | HTR2C (0.44) | HTR2CHTR2AKDM4EALDH1A1TSHR | |
| SCHEMBL4625971 | 0.72 | HTR2C (0.36) | HTR2CHTR2AKDM4EALDH1A1TSHR | |
| SCHEMBL2400816 | 0.64 | KDM4E (0.49) | HTR2CHTR2AKDM4EALDH1A1TSHR | |
| SCHEMBL31217582 | 0.61 | ALDH1A1 (0.47) | HTR2CHTR2AKDM4EALDH1A1TSHR | |
| SCHEMBL13250621 | 0.61 | ESR1 (0.46) | HTR2CHTR2AKDM4EALDH1A1TSHR | |
| SCHEMBL10298951 | 0.61 | ALDH1A1 (0.60) | HTR2CHTR2AKDM4EALDH1A1TSHR | |
| SCHEMBL16284358 | 0.60 | ALDH1A1 (0.46) | KDM4EALDH1A1TSHRHPGDHTT | |
| SCHEMBL13250629 | 0.59 | DNMT1 (0.41) | HTR2CHTR2AKDM4EALDH1A1TSHR | |
| SCHEMBL14144031 | 0.57 | ALDH1A1 (0.50) | KDM4EALDH1A1HPGDHTTMEN1 | |
| SCHEMBL12865358 | 0.57 | DNMT1 (0.46) | HTR2CHTR2AKDM4EALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696582-B1 | Polycyclic spirophthalimide derivatives, process for their preparation and their use as fulgimides | TOKUYAMA CORP (JP) | 2000-03-22 | — | — | EP | disclosed |
| US-5631382-A | PHOTOCHROMIC LENSES | TOKUYAMA CORPORATION (JP) | 1997-05-20 | — | — | US | disclosed |
| EP-0696582-A1 | Polycyclic spirophthalimide derivatives, process for their preparation and their use as fulgimides | TOKUYAMA CORPORATION (JP) | 1996-02-14 | — | — | EP | disclosed |