SCHEMBL4625971

SCHEMBL4625971

C1=CC2(Oc3c1ccc1ccccc31)C1CCCC2CCC1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 3/20 0.36
HTR2A P28223 2/20 0.36
SLC6A2 P23975 2/20 0.32
SLC6A4 P31645 2/20 0.32
SLC6A3 Q01959 2/20 0.32
CYP1B1 Q16678 2/20 0.32
ALDH1A1 P00352 4/20 0.31
KDM4E B2RXH2 3/20 0.31
HSD17B10 Q99714 3/20 0.31
TSHR P16473 2/20 0.31
MEN1 O00255 2/20 0.31
MAPT P10636 2/20 0.31
HPGD P15428 2/20 0.31
KMT2A Q03164 2/20 0.31
HTR1A P08908 1/20 0.31
HTR7 P34969 1/20 0.31
HTR2B P41595 1/20 0.31
TMEM97 Q5BJF2 1/20 0.31
SIGMAR1 Q99720 1/20 0.31
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8823964 0.84 HTR2C (0.31) HTR2CHTR2A
SCHEMBL14631751 0.84 SLC6A2 (0.31) HTR2CHTR2ASLC6A2SLC6A4SLC6A3
SCHEMBL2400816 0.77 KDM4E (0.49) HTR2CHTR2ASLC6A2SLC6A4SLC6A3
SCHEMBL9035829 0.75 HTR2C (0.34) HTR2CHTR2ACYP19A1
SCHEMBL8681014 0.75 ALDH1A1 (0.39) HTR2CHTR2ACYP1B1ALDH1A1KDM4E
SCHEMBL4538261 0.74 HTR2C (0.34) HTR2CHTR2A
SCHEMBL29756154 0.74 HTR2C (0.34) HTR2CHTR2A
SCHEMBL8136351 0.72 HTR2C (0.42) HTR2CHTR2ASLC6A2SLC6A4SLC6A3
SCHEMBL15196167 0.72 ALDH1A1 (0.37) CYP1B1ALDH1A1KDM4EHSD17B10TSHR
SCHEMBL9917550 0.72 HSD17B10 (0.43) ALDH1A1KDM4EHSD17B10TSHRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-11246626-A None JP disclosed
EP-3521907-B1 PHOTOCHROMIC LENS AND POLYMERIZABLE COMPOSITION MITSUI CHEMICALS INC (JP) 2024-12-04 EP disclosed
EP-3438147-B1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIAL, OPTICAL MATERIAL OBTAINED FROM COMPOSITION, AND PLASTIC LENS MITSUI CHEMICALS INC (JP) 2023-06-21 EP disclosed
US-11472943-B2 Polymerizable composition for optical material, optical material, and application thereof MITSUI CHEMICALS, INC. (JP) 2022-10-18 US disclosed
CN-110831992-B Polymerizable composition for optical material and molded article 三井化学株式会社 2022-08-23 CN disclosed
US-11414515-B2 Polymerizable composition for optical material and optical material and plastic lens obtainable from same composition MITSUI CHEMICALS, INC. (JP) 2022-08-16 US disclosed
CN-109689698-B Polymerizable composition for optical material and molded article 三井化学株式会社 2022-05-31 CN disclosed
EP-3521322-B1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIALS, AND MOLDED BODY MITSUI CHEMICALS INC (JP) 2022-03-09 EP disclosed
US-11248077-B2 Polymerizable composition for optical material and molded product MITSUI CHEMICALS, INC. (JP) 2022-02-15 US disclosed
US-20210054126-A1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIAL AND MOLDED PRODUCT MITSUI CHEMICALS, INC. (JP) 2021-02-25 US disclosed
EP-0773272-B1 PHOTOCHROMIC CURABLE COMPOSITION TOKUYAMA CORP (JP) 1999-09-15 EP disclosed
JP-H11246626-A PHOTOCHROMIC HARDENABLE COMPOSITION TOKUYAMA CORP 1999-09-14 JP disclosed
EP-0940694-A1 Photochromic curable composition TOKUYAMA CORPORATION (JP) 1999-09-08 EP disclosed
EP-0773271-B1 PROCESS FOR THE PRODUCTION OF PHOTOCHROMIC PRODUCT OF CURING TOKUYAMA CORP (JP) 1999-07-21 EP disclosed
EP-0900798-A1 FULGIMIDE COMPOUNDS, USE OF THEM, AND COMPOSITIONS CONTAINING THE SAME TOKUYAMA CORPORATION (JP) 1999-03-10 EP disclosed
US-5631382-A PHOTOCHROMIC LENSES TOKUYAMA CORPORATION (JP) 1997-05-20 US disclosed
EP-0773273-A1 PROCESS FOR THE PRODUCTION OF PHOTOCHROMIC PRODUCT OF CURING TOKUYAMA CORPORATION (JP) 1997-05-14 EP disclosed
EP-0773272-A1 PHOTOCHROMIC CURABLE COMPOSITION TOKUYAMA CORPORATION (JP) 1997-05-14 EP disclosed
EP-0773271-A1 PROCESS FOR THE PRODUCTION OF PHOTOCHROMIC PRODUCT OF CURING TOKUYAMA CORPORATION (JP) 1997-05-14 EP disclosed
EP-0696582-A1 Polycyclic spirophthalimide derivatives, process for their preparation and their use as fulgimides TOKUYAMA CORPORATION (JP) 1996-02-14 EP disclosed