Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | BRD2 | P25440 | 1/20 | 0.40 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8134400 | 0.96 | POLB (0.43) | POLBKMT2AMEN1GAAHSD17B10 | |
| SCHEMBL8133737 | 0.89 | EGFR (0.43) | POLBKMT2AMEN1GAAHSD17B10 | |
| SCHEMBL8135123 | 0.89 | EGFR (0.43) | POLBKMT2AMEN1GAAHSD17B10 | |
| SCHEMBL8125776 | 0.88 | EGFR (0.42) | POLBKMT2AMEN1GAAHSD17B10 | |
| SCHEMBL6609340 | 0.87 | CASP3 (0.47) | KMT2AMEN1HSD17B10KDM4EUSP2 | |
| SCHEMBL5103002 | 0.85 | MEN1 (0.43) | POLBKMT2AMEN1GAAHSD17B10 | |
| SCHEMBL5103008 | 0.85 | MEN1 (0.43) | POLBKMT2AMEN1GAAHSD17B10 | |
| SCHEMBL14287056 | 0.85 | MEN1 (0.43) | POLBKMT2AMEN1GAAHSD17B10 | |
| SCHEMBL8140122 | 0.82 | HTR6 (0.39) | GAAALDH1A1TSHRL3MBTL1 | |
| SCHEMBL8134085 | 0.82 | LSS (0.46) | POLBKMT2AMEN1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0781285-B1 | FUSED INDOLE AND QUINOXALINE DERIVATIVES, THEIR PREPARATION AND USE AS GLUTAMATE ANTAGONISTS | NEUROSEARCH AS (DK) | 2000-01-12 | — | — | EP | disclosed |
| US-5801174-A | CEREBROVASCULAR DISORDERS | NEUROSEARCH A/S (DK) | 1998-09-01 | — | — | US | disclosed |