SCHEMBL8137339

SCHEMBL8137339

Nc1c(C(F)(F)F)cc(F)c(Oc2cc(F)c(C(F)(F)F)c(Oc3c(F)cc(C(F)(F)F)c(N)c3F)c2F)c1F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8146226 0.89
SCHEMBL8144351 0.88
SCHEMBL8152748 0.84
SCHEMBL8138538 0.83 HTR2A (0.31)
SCHEMBL8151980 0.82
SCHEMBL8151983 0.82 KDM4E (0.34)
SCHEMBL8147871 0.82 TSHR (0.31)
SCHEMBL8152404 0.82 KDM4E (0.31)
SCHEMBL8152406 0.82 KIF11 (0.33)
SCHEMBL8146633 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6103860-A LOW DIELECTRIC CONSTANT, EXCELLENT TRANSPARENCY, LOW HYGROSCOPICITY AND EXCELLENT PROCESSABILITY; SUBSTRATE FOR AN OPTICAL DISK, A PICK-UP LENS, A PLASTIC SUBSTRATE FOR A LIQUID CELL AND A PRISM MITSUI CHEMICALS, INC. (JP) 2000-08-15 US disclosed
US-5990261-A Organic optical component MITSUI CHEMICALS, INC. (JP) 1999-11-23 US disclosed
EP-0826717-A1 An organic optical component MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1998-03-04 EP disclosed