Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8144292 | 0.91 | NR4A1 (0.37) | MAPTPOLBHSP90AA1NR4A1RAB9A | |
| SCHEMBL8144265 | 0.85 | MAPT (0.38) | MAPTPOLBHSP90AA1NR4A1KDM4E | |
| SCHEMBL8152685 | 0.82 | L3MBTL1 (0.35) | MAPTPOLBHSP90AA1NR4A1KDM4E | |
| SCHEMBL8147090 | 0.81 | AR (0.36) | MAPTPOLBHSP90AA1NR4A1RAB9A | |
| SCHEMBL8148126 | 0.81 | MAPT (0.41) | MAPTPOLBHSP90AA1NR4A1KDM4E | |
| SCHEMBL8147527 | 0.81 | L3MBTL1 (0.35) | MAPTPOLBHSP90AA1NR4A1KDM4E | |
| SCHEMBL8146765 | 0.79 | MAPT (0.37) | MAPTHSP90AA1NR4A1KDM4ERAB9A | |
| SCHEMBL8146677 | 0.78 | NR4A1 (0.37) | MAPTPOLBHSP90AA1NR4A1RAB9A | |
| SCHEMBL8138761 | 0.78 | L3MBTL1 (0.38) | MAPTPOLBHSP90AA1NR4A1KDM4E | |
| SCHEMBL8144453 | 0.77 | MAPT (0.36) | MAPTPOLBHSP90AA1KDM4ECRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6103860-A | LOW DIELECTRIC CONSTANT, EXCELLENT TRANSPARENCY, LOW HYGROSCOPICITY AND EXCELLENT PROCESSABILITY; SUBSTRATE FOR AN OPTICAL DISK, A PICK-UP LENS, A PLASTIC SUBSTRATE FOR A LIQUID CELL AND A PRISM | MITSUI CHEMICALS, INC. (JP) | 2000-08-15 | — | — | US | disclosed |
| US-5990261-A | Organic optical component | MITSUI CHEMICALS, INC. (JP) | 1999-11-23 | — | — | US | disclosed |
| EP-0826717-A1 | An organic optical component | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1998-03-04 | — | — | EP | disclosed |