Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9046549 | 0.90 | LMNA (0.39) | ALDH1A1HTTLMNAKMT2AMEN1 | |
| SCHEMBL8130741 | 0.90 | LMNA (0.51) | ALDH1A1LMNAKMT2AMEN1KDM4E | |
| SCHEMBL6211765 | 0.89 | LMNA (0.42) | ALDH1A1LMNAKMT2AMEN1KDM4E | |
| SCHEMBL9045182 | 0.86 | NPC1 (0.40) | ALDH1A1HTTLMNAKMT2AMEN1 | |
| SCHEMBL8137475 | 0.84 | ALDH1A1 (0.61) | ALDH1A1HTTLMNAKMT2AMEN1 | |
| SCHEMBL10911343 | 0.84 | ALDH1A1 (0.54) | ALDH1A1HTTLMNAKDM4EHPGD | |
| SCHEMBL9046429 | 0.82 | KMT2A (0.36) | ALDH1A1HTTLMNAKMT2AMEN1 | |
| SCHEMBL9055165 | 0.81 | LMNA (0.40) | ALDH1A1LMNAKMT2AMEN1KDM4E | |
| SCHEMBL6214250 | 0.80 | LMNA (0.45) | ALDH1A1LMNAKMT2AMEN1KDM4E | |
| SCHEMBL8130462 | 0.80 | LMNA (0.47) | ALDH1A1LMNAKMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0401623-B1 | Process for the preparation of 7-(3-amino- and 3-aminomethyl-1-pyrrolidinyl)-3-quinolinonecarboxylic and -naphthyridinonecarboxylic acids | BAYER AG (DE) | 2000-01-26 | — | — | EP | disclosed |
| EP-0422485-B1 | Quinolone carboxylic acid derivatives, process for their preparation and their use | BAYER AG (DE) | 1996-04-03 | — | — | EP | disclosed |
| EP-0422485-A2 | Quinolone carboxylic acid derivatives, process for their preparation and their use | BAYER AG (DE) | 1991-04-17 | — | — | EP | disclosed |
| EP-0401623-A1 | Process for the preparation of 7-(3-amino- and 3-aminomethyl-1-pyrrolidinyl)-3-quinolinonecarboxylic and -naphthyridinonecarboxylic acids | BAYER AG (DE) | 1990-12-12 | — | — | EP | disclosed |