SCHEMBL813807

SCHEMBL813807

CCCCOC(=O)C1CCC(=O)N1

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.50
GAA P10253 1/20 0.48
CNR1 P21554 1/20 0.46
DAGLA Q9Y4D2 1/20 0.46
TSHR P16473 2/20 0.41
CRBN Q96SW2 3/20 0.40
ALDH1A1 P00352 1/20 0.39
POLB P06746 2/20 0.38
KMT2A Q03164 1/20 0.38
DDB1 Q16531 1/20 0.37
ATM Q13315 1/20 0.37
NAAA Q02083 2/20 0.37
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6205684 1.00 LMNA (0.50) LMNAGAACNR1DAGLATSHR
SCHEMBL12909848 1.00 LMNA (0.50) LMNAGAACNR1DAGLATSHR
SCHEMBL6686850 0.95 LMNA (0.49) LMNAGAACNR1DAGLATSHR
SCHEMBL6686852 0.95 LMNA (0.49) LMNAGAACNR1DAGLATSHR
SCHEMBL10353311 0.94 CNR1 (0.49) LMNAGAACNR1DAGLATSHR
SCHEMBL9511157 0.94 CNR1 (0.49) LMNAGAACNR1DAGLATSHR
SCHEMBL10353701 0.94 CNR1 (0.49) LMNAGAACNR1DAGLATSHR
SCHEMBL1978843 0.94 CNR1 (0.49) LMNAGAACNR1DAGLATSHR
SCHEMBL1978841 0.94 CNR1 (0.49) LMNAGAACNR1DAGLATSHR
SCHEMBL7715586 0.94 CNR1 (0.49) LMNAGAACNR1DAGLATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119280226-A Application of butyl pyroglutamate in preparation of anti-Alzheimer disease drugs 江西农业大学 2025-01-10 CN claimed
CN-119280225-A Application of butyl pyroglutamate in preparation of antihypertensive drugs 江西农业大学 2025-01-10 CN claimed
CN-102711455-A Biocide compositions comprising derivatives of pyroglutamic acid COGNIS IP MAN GMBH 2012-10-03 CN claimed
US-20100163070-A1 METHOD FOR STRAIGHTENING KERATINOUS FIBRES USING HEATING MEANS AND AN AMIDE L'OREAL S.A. (FR) 2010-07-01 US claimed
EP-0397519-B1 Cosmetic composition UNILEVER PLC (GB) 1994-11-09 EP claimed
EP-0342056-B1 Cosmetic composition UNILEVER PLC (GB) 1994-08-17 EP claimed
EP-0277428-B1 Cosmetic composition UNILEVER PLC (GB) 1994-03-23 EP claimed
EP-0342055-B1 Use of pyroglutamic acid alkyl esters for the manufacture of a medicament for the treatment of ichthyosis UNILEVER PLC (GB) 1994-01-12 EP claimed
EP-0342054-B1 Cosmetic composition UNILEVER PLC (GB) 1993-11-03 EP claimed
US-5137714-A Anhydrous cosmetic composition comprising stable lower alkyl esters of pyroglutamic acid UNILEVER PATENT HOLDINGS B.V. (NL) 1992-08-11 US claimed
EP-0397519-A1 Cosmetic composition UNILEVER PLC (GB) 1990-11-14 EP claimed
EP-0342055-A2 Use of pyroglutamic acid alkyl esters for the manufacture of a medicament for the treatment of ichthyosis UNILEVER PLC (GB) 1989-11-15 EP claimed
EP-0342054-A2 Cosmetic composition UNILEVER PLC (GB) 1989-11-15 EP claimed
EP-0342056-A2 Cosmetic composition UNILEVER PLC (GB) 1989-11-15 EP claimed
EP-0277428-A2 Cosmetic composition UNILEVER PLC (GB) 1988-08-10 EP claimed
US-12619006-B2 Wavelength selective absorption filter and display device FUJIFILM CORPORATION (JP) 2026-05-05 US disclosed
CN-116568763-B Wavelength selective absorption filter and display device 富士胶片株式会社 2025-05-13 CN disclosed
EP-0295092-A2 Skin treatment composition UNILEVER PLC (GB) 1988-12-14 EP disclosed
EP-0277428-A2 Cosmetic composition UNILEVER PLC (GB) 1988-08-10 EP disclosed
EP-0272920-A1 Cosmetic composition UNILEVER PLC (GB) 1988-06-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12619006-B2 Wavelength selective absorption filter and display device STRA6, SULT1A1, SLC7A1 LMNA 2969/4885GAA 2501/4885CNR1 660/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.