Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | NR1H4 | Q96RI1 | 6/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | SELL | P14151 | 2/20 | 0.53 |
| ▸ | SELP | P16109 | 2/20 | 0.53 |
| ▸ | SELE | P16581 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4104833 | 0.85 | KMT2A (0.62) | KMT2ANR1H4EPHX2ALDH1A1SELL | |
| SCHEMBL7314826 | 0.83 | KMT2A (0.71) | KMT2ACYP2C9CYP2C19NR1H4EPHX2 | |
| Hydrochloric Acid SCHEMBL3883713 | 0.83 | KMT2A (0.61) | KMT2ANR1H4EPHX2ALDH1A1SELL | |
| SCHEMBL81511 | 0.81 | CYP2C19 (0.64) | KMT2ACYP2C9CYP2C19ALDH1A1MEN1 | |
| SCHEMBL9104129 | 0.81 | KMT2A (0.62) | KMT2ANR1H4EPHX2ALDH1A1SELL | |
| SCHEMBL28416786 | 0.81 | ST14 (0.56) | KMT2ACYP2C19ALDH1A1 | |
| SCHEMBL5374862 | 0.80 | KMT2A (1.00) | KMT2ANR1H4EPHX2ALDH1A1SELL | |
| SCHEMBL3932787 | 0.80 | KMT2A (0.67) | KMT2ANR1H4EPHX2ALDH1A1SELL | |
| SCHEMBL13920454 | 0.80 | KMT2A (0.67) | KMT2ANR1H4EPHX2ALDH1A1SELL | |
| SCHEMBL22253411 | 0.79 | LOXL2 (0.62) | KMT2ACYP2C9CYP2C19ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115353667-A | Method and material for reducing waste | 李蓁蓁 | 2022-11-18 | — | — | CN | disclosed |
| US-6114390-A | AN ARGININAMIDE OR ORNITHINAMIDE COMPOUND AS TREATING MEMORY LOSS, MIGRAINE, SLEEP DISORDERS, PAIN, CARDIOVASCULAR DISEASES, SUBARACHNOIDAL BLEEDING, VASCULAR-HYPERTROPHIC CHANGES, CEREBRAL AND CORONARY VASOSPASMS | KARL THOMAE GMBH (DE) | 2000-09-05 | — | — | US | disclosed |
| EP-0885186-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | Dr. Karl Thomae GmbH (DE) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997019911-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1997-06-05 | — | — | WO | disclosed |