Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 3/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | RARB | P10826 | 2/20 | 0.46 |
| ▸ | ESRRG | P62508 | 1/20 | 0.45 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.45 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10604135 | 0.86 | ST14 (0.61) | ST14LMNAHTTCA2CA9 | |
| Hydrochloric Acid SCHEMBL7327788 | 0.84 | ST14 (0.59) | ST14LMNAHTTCA2CA9 | |
| SCHEMBL1439724 | 0.82 | CA12 (0.63) | LMNACA2CA9CA12CA1 | |
| SCHEMBL27617137 | 0.82 | CA2 (0.62) | ST14LMNAHTTCA2CA9 | |
| SCHEMBL3654946 | 0.82 | CA2 (0.52) | ST14LMNAHTTCA2CA9 | |
| SCHEMBL27711422 | 0.81 | LMNA (0.51) | ST14LMNAHTTCA2CA9 | |
| SCHEMBL3523937 | 0.81 | KDM4E (0.68) | LMNAHTTKMT2AHDAC2HDAC8 | |
| SCHEMBL5452418 | 0.81 | ALDH1A1 (0.57) | ST14LMNAHTTCA2CA9 | |
| SCHEMBL625333 | 0.81 | ESRRG (0.55) | ST14LMNACA2CA9CA12 | |
| SCHEMBL8142404 | 0.81 | MCHR1 (0.54) | ST14LMNACA2CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107001286-B | Dihydropyrimidine-2-one compounds and medicinal use thereof | 日本烟草产业株式会社 | 2020-07-07 | — | — | CN | disclosed |