SCHEMBL8138228

SCHEMBL8138228

C=CC(=O)OC(C)(O)CO

nearest known ligand 0.45

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.45
TP53 P04637 3/20 0.45
HIF1A Q16665 3/20 0.45
CYP3A4 P08684 2/20 0.45
MAPK1 P28482 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
TSHR P16473 8/20 0.40
HPGD P15428 1/20 0.36
HSD17B10 Q99714 1/20 0.35
THRB P10828 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27502718 0.83 TSHR (0.38) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL466005 0.83 THRB (0.42) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL8138225 0.83 TSHR (0.38) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL7924485 0.81 ALDH1A1 (0.44) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL1374290 0.80 ALDH1A1 (0.47) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL27551478 0.79 ALDH1A1 (0.50) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL28073426 0.79 TSHR (0.42) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL28042819 0.79 TSHR (0.35) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL30601951 0.79 ALDH1A1 (0.57) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL11801011 0.79 ALDH1A1 (0.42) ALDH1A1TP53HIF1ACYP3A4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118717532-A Preparation method of self-acid etching dental adhesive material 北京市春立正达医疗器械股份有限公司 2024-10-01 CN claimed
CN-112074232-A Improved diffusion layer for in-vivo enzymatic sensors 豪夫迈·罗氏有限公司 2020-12-11 CN claimed
US-6106997-A PRINTING DURABILITY, IMAGE REPRODUCIBILITY AND STORAGE STABILITY TORAY INDUSTRIES, INC. (JP) 2000-08-22 US claimed
EP-0298611-B1 POLYURETHANES AND POLYURETHANE/POLYUREAS CROSSLINKED USING 2-GLYCERYL ACRYLATE OR 2-GLYCERYL METHACRYLATE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-08-04 EP claimed
EP-0298611-A2 Polyurethanes and polyurethane/polyureas crosslinked using 2-glyceryl acrylate or 2-glyceryl methacrylate MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-01-11 EP claimed
US-4786657-A BINDERS, DRESSINGS, MEMBRANES, PROTECTIVE COATINGS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-11-22 US claimed
WO-2024198017-A1 NEGATIVE PHOTOSENSITIVE POLYIMIDE PRECURSOR RESIN COMPOSITION 深圳先进电子材料国际创新研究院 2024-10-03 WO disclosed
CN-118717532-A Preparation method of self-acid etching dental adhesive material 北京市春立正达医疗器械股份有限公司 2024-10-01 CN disclosed
CN-118717532-A Preparation method of self-acid etching dental adhesive material 北京市春立正达医疗器械股份有限公司 2024-10-01 CN disclosed
CN-112074232-A Improved diffusion layer for in-vivo enzymatic sensors 豪夫迈·罗氏有限公司 2020-12-11 CN disclosed
CN-1046882-C Abrasive articles comprising a grinding aid dispersed in a polymeric blend binder MINNESOTA MINING & MFG (US) 1999-12-01 CN disclosed
EP-0657876-B1 Magnetic recording medium comprising binder that may be cured using both isocyanate and radiation curing techniques MINNESOTA MINING & MFG (US) 1997-09-17 EP disclosed
EP-0643866-B1 MAGNETIC RECORDING MEDIUM COMPRISING BINDER THAT MAY BE CURED USING BOTH ISOCYANATE AND RADIATION CURING TECHNIQUES MINNESOTA MINING & MFG (US) 1996-10-30 EP disclosed
EP-0298611-A2 Polyurethanes and polyurethane/polyureas crosslinked using 2-glyceryl acrylate or 2-glyceryl methacrylate MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-01-11 EP disclosed
EP-0298611-A2 Polyurethanes and polyurethane/polyureas crosslinked using 2-glyceryl acrylate or 2-glyceryl methacrylate MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-01-11 EP disclosed
US-4786657-A BINDERS, DRESSINGS, MEMBRANES, PROTECTIVE COATINGS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-11-22 US disclosed
US-4786657-A BINDERS, DRESSINGS, MEMBRANES, PROTECTIVE COATINGS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-11-22 US disclosed
US-4786657-A BINDERS, DRESSINGS, MEMBRANES, PROTECTIVE COATINGS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-11-22 US disclosed
US-4650743-A PHOTOPOLYMERIZED HYDROZYALKYL ACRYLATE AND OLIGOMER E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-03-17 US disclosed
EP-0210638-A2 Optical coating composition E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-02-04 EP disclosed