Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.37 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.37 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5175344 | 0.89 | NPC1 (0.40) | KMT2ANPC1RAB9ATBXAS1CYP3A4 | |
| SCHEMBL27352543 | 0.84 | — | — | |
| SCHEMBL8736180 | 0.84 | TBXAS1 (0.47) | KMT2ANPC1RAB9ATBXAS1LMNA | |
| SCHEMBL1237700 | 0.82 | NPC1 (0.43) | KMT2ANPC1RAB9ATBXAS1HDAC3 | |
| SCHEMBL28848958 | 0.81 | NPC1 (0.40) | KMT2ANPC1RAB9ATBXAS1HDAC3 | |
| SCHEMBL7574578 | 0.81 | NPC1 (0.46) | KMT2ANPC1RAB9ATBXAS1TSHR | |
| SCHEMBL10997776 | 0.81 | TBXAS1 (0.49) | KMT2ANPC1RAB9ATBXAS1TSHR | |
| SCHEMBL29163121 | 0.79 | NPC1 (0.47) | KMT2ANPC1RAB9ATBXAS1HDAC1 | |
| SCHEMBL13255601 | 0.79 | KMT2A (0.42) | KMT2ANPC1RAB9ATBXAS1HDAC3 | |
| SCHEMBL7472243 | 0.79 | NPC1 (0.45) | KMT2ANPC1RAB9ATBXAS1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6090842-A | REDUCES CONCENTRATION OF OXYGEN IN CELLS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-07-18 | — | — | US | claimed |