Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL814054 | 0.81 | CNR2 (0.33) | — | |
| SCHEMBL813926 | 0.80 | ADORA3 (0.36) | ADORA3ADORA2AADORA2BADORA1KDM4E | |
| SCHEMBL814113 | 0.80 | PSMB5 (0.36) | ADORA3ADORA2AADORA1KDM4E | |
| SCHEMBL814162 | 0.79 | MAPT (0.38) | ADORA3ADORA2AADORA1KDM4E | |
| SCHEMBL12460354 | 0.78 | RAB9A (0.36) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL813984 | 0.78 | ADORA3 (0.36) | ADORA3ADORA2AADORA2BADORA1KDM4E | |
| SCHEMBL813989 | 0.77 | NPC1 (0.34) | ADORA3ADORA2AADORA1KDM4E | |
| SCHEMBL814050 | 0.77 | MAPT (0.44) | ADORA3ADORA2AADORA2BADORA1KDM4E | |
| SCHEMBL814386 | 0.77 | NPC1 (0.36) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL813790 | 0.77 | MAPT (0.38) | ADORA3ADORA2AADORA1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1789459-B1 | POLYOLEFINS | INEOS SALES UK LTD (GB) | 2014-04-30 | — | — | EP | disclosed |
| US-8067328-B2 | Polymerisation and oligomerisation catalysts | INEOS EUROPE LIMITED (GB) | 2011-11-29 | — | — | US | disclosed |
| US-8067328-B2 | Polymerisation and oligomerisation catalysts | INEOS EUROPE LIMITED (GB) | 2011-11-29 | — | — | US | disclosed |
| US-7989565-B2 | Polyolefins | INEOS EUROPE LIMITED (GB) | 2011-08-02 | — | — | US | disclosed |
| US-7989565-B2 | Polyolefins | INEOS EUROPE LIMITED (GB) | 2011-08-02 | — | — | US | disclosed |
| US-20090124487-A1 | Polyolefins | BARCLAYS BANK PLC (GB) | 2009-05-14 | — | — | US | disclosed |
| US-20090124487-A1 | Polyolefins | BARCLAYS BANK PLC (GB) | 2009-05-14 | — | — | US | disclosed |
| US-20070207918-A1 | Polymerisation and Oligomerisation Catalysts | INEOS SALES (UK) LIMITED (GB) | 2007-09-06 | — | — | US | disclosed |
| US-20070207918-A1 | Polymerisation and Oligomerisation Catalysts | INEOS SALES (UK) LIMITED (GB) | 2007-09-06 | — | — | US | disclosed |
| US-7229943-B2 | Polymerisation and oligomerisation catalysts | INNOVENE EUROPE LIMITED (GB) | 2007-06-12 | — | — | US | disclosed |
| US-7229943-B2 | Polymerisation and oligomerisation catalysts | INNOVENE EUROPE LIMITED (GB) | 2007-06-12 | — | — | US | disclosed |