Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 2/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HMGCR | P04035 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 7/20 | 0.32 |
| ▸ | ACLY | P53396 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 4/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Norflurane SCHEMBL5935148 | 0.81 | CASP1 (0.35) | FFAR3ALDH1A1HMGCRCHRM1TBXA2R | |
| Trifluoroacetic Acid SCHEMBL20527475 | 0.79 | FFAR3 (0.62) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Trifluoroacetic Acid SCHEMBL4485807 | 0.79 | FFAR3 (0.62) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Propionic Acid SCHEMBL7625676 | 0.78 | FFAR3 (0.71) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Propionic Acid SCHEMBL27310283 | 0.77 | — | — | |
| Propionic Acid SCHEMBL1331605 | 0.77 | — | — | |
| Propionic Acid SCHEMBL1462509 | 0.77 | FFAR3 (1.00) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Propionic Acid SCHEMBL11661434 | 0.77 | FFAR3 (1.00) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Propionic Acid SCHEMBL1332599 | 0.77 | — | — | |
| Propionic Acid SCHEMBL19409 | 0.77 | FFAR3 (1.00) | FFAR3HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6013245-A | Aerosol formulation containing beclomethasone dipropionate and 1,1,1,2,3,3,3-heptafluoro-n-propane as propellant | GLAXO GROUP LIMITED (GB) | 2000-01-11 | — | — | US | disclosed |
| US-5833950-A | Aerosol formulations containing beclomethasone dipropionate-1, 1, 1, 2-tetrafluoroethane solvate | GLAXO GROUP LIMITED (GB) | 1998-11-10 | — | — | US | disclosed |
| EP-0658101-B1 | SURFACTANT FREE AEROSOL FORMULATIONS CONTAINING BECLOMETHASONE DIPROPIONATE | GLAXO GROUP LTD (GB) | 1998-01-28 | — | — | EP | disclosed |
| EP-0775484-A1 | Surfactant free aerosol formulations containing bezlomethsone dipropionate | GLAXO GROUP LIMITED (GB) | 1997-05-28 | — | — | EP | disclosed |
| EP-0658101-A1 | SURFACTANT FREE AEROSOL FORMULATIONS CONTAINING BECLOMETHASONE DIPROPIONATE | GLAXO GROUP LIMITED (GB) | 1995-06-21 | — | — | EP | disclosed |
| WO-1994003153-A1 | SURFACTANT FREE AEROSOL FORMULATIONS CONTAINING BECLOMETHASONE DIPROPIONATE | GLAXO GROUP LIMITED (GB) | 1994-02-17 | — | — | WO | disclosed |