SCHEMBL81395

SCHEMBL81395

ClCc1cccc(Oc2ccccc2)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 1/20 0.54
ALDH1A1 P00352 5/20 0.50
KDM4E B2RXH2 4/20 0.50
HTT P42858 3/20 0.50
TSHR P16473 2/20 0.50
TDP1 Q9NUW8 1/20 0.50
LTA4H P09960 1/20 0.50
HPGD P15428 1/20 0.50
MAOB P27338 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
MITF O75030 1/20 0.47
POLB P06746 1/20 0.47
MAPK1 P28482 1/20 0.47
MMP1 P03956 2/20 0.47
PPARG P37231 1/20 0.47
PPARA Q07869 1/20 0.47
HSD17B10 Q99714 1/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
MMP2 P08253 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30132325 1.00 TTR (0.54) TTRALDH1A1KDM4EHTTTSHR
Fluoride SCHEMBL27414212 0.98 TTR (0.53) TTRALDH1A1KDM4EHTTTSHR
SCHEMBL18422515 0.94 TTR (0.46) TTRALDH1A1KDM4EHTTTSHR
SCHEMBL11178465 0.91 SRD5A2 (0.51) TTRALDH1A1KDM4EHTTTDP1
SCHEMBL11169763 0.91 FFAR1 (0.48) TTRALDH1A1KDM4EHTTTDP1
Pyridine SCHEMBL11784297 0.89 TRPV6 (0.52) TTRALDH1A1KDM4EHTTTSHR
SCHEMBL11182709 0.88 FFAR1 (0.58) MAOBSMN1; SMN2
SCHEMBL11318601 0.86 ALDH1A1 (0.56) TTRALDH1A1KDM4EHTTHPGD
SCHEMBL11313737 0.85 MAPT (0.42) TTRALDH1A1KDM4EHTTTDP1
SCHEMBL2937730 0.85 ALDH1A1 (0.60) TTRALDH1A1KDM4EHTTLTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 481 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115769826-A Archival repository insecticide 云南春城档案用品有限公司 2023-03-10 CN claimed
EP-0161827-A1 Novel intermediate for the preparation of cyclopropane carboxylate esters and its preparation and use INDIAN EXPLOSIVES LIMITED (IN) 1985-11-21 EP claimed
US-4377713-A CHLORINATION OF M-PHENOXYTOLUENE, BY-PRODUCT INHIBITION ETHYL CORPORATION (US) 1983-03-22 US claimed
US-4317934-A Preparation of carbonyl compounds ETHYL CORPORATION (US) 1982-03-02 US claimed
EP-0012214-B1 PROCESS FOR THE PREPARATION OF 3-PHENOXYBENZYL ALCOHOLS BAYER AG (DE) 1981-08-26 EP claimed
US-4250340-A CHLORINATING M-PHENOXYTOLUENE WITH SULFURYL CHLORIDE USING ALKYL PERALKANOATE INITIATOR CRODA SYNTHETIC CHEMICALS LIMITED (GB) 1981-02-10 US claimed
EP-0012214-A1 Process for the preparation of 3-phenoxybenzyl alcohols BAYER AG (DE) 1980-06-25 EP claimed
US-4146737-A BY SULFURYL CHLORIDE, FREE RADICAL INITIATOR SHELL OIL COMPANY (US) 1979-03-27 US claimed
JP-61053291-A None JP disclosed
JP-60123491-A None JP disclosed
JP-56135440-A None JP disclosed
JP-56166142-A None JP disclosed
US-20250353863-A1 TRICYCLIC SPIROLACTAM COMPOUNDS WITH ANTIMYCOBACTERIAL ACTIVITY INST NAT SANTE RECH MED (FR) 2025-11-20 US disclosed
CN-119684287-A 4- (3- (Piperidin-4-yl) -1H-pyrazol-5-yl) -1H-pyrrole [2,3-b ] pyridine derivative, and preparation method and application thereof 烟台新药创制山东省实验室 2025-03-25 CN disclosed
EP-0003066-A2 Process for the preparation of meta-aryloxybenzaldehydes, and meta- aryloxybenzaldehydes produced by the process SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1979-07-25 EP disclosed
US-4161537-A Insecticidal isovaleric acid esters Dainippon Jochugiki Kabushiki Kaisha (JP) 1979-07-17 US disclosed
US-4146737-A BY SULFURYL CHLORIDE, FREE RADICAL INITIATOR SHELL OIL COMPANY (US) 1979-03-27 US disclosed
EP-0000345-A1 Substituted phenoxybenzyloxycarbonyl derivatives, their preparation and their use as insecticides and acaricides BAYER AG (DE) 1979-01-24 EP disclosed
US-4014940-A Process for preparing m-phenoxybenzylalcohol and side-chain halogenated m-phenoxytoluene SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-03-29 US disclosed
US-3969393-A Process for preparing cyclopropane-carboxylic acid esters SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-07-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250353863-A1 TRICYCLIC SPIROLACTAM COMPOUNDS WITH ANTIMYCOBACTERIAL ACTIVITY TALDO1, TBCA, TBCD TTR 1010/4885ALDH1A1 1586/4885KDM4E 4585/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.