Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 5/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 3/20 | 0.35 |
| ▸ | MC4R | P32245 | 1/20 | 0.34 |
| ▸ | MC5R | P33032 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3697218 | 0.89 | DPP4 (0.47) | PARP1NR1H2DPP4DPP7NR1H3 | |
| SCHEMBL25913721 | 0.89 | DPP4 (0.47) | PARP1NR1H2DPP4DPP7NR1H3 | |
| SCHEMBL1673503 | 0.88 | MEN1 (0.43) | PARP1NR1H2NR1H3ALDH1A1MAPT | |
| SCHEMBL28304239 | 0.88 | NR1H2 (0.50) | PARP1NR1H2DPP4DPP7NR1H3 | |
| SCHEMBL27909454 | 0.87 | PARP1 (0.42) | PARP1NR1H2DPP4DPP7NR1H3 | |
| SCHEMBL30385469 | 0.87 | PARP1 (0.42) | PARP1NR1H2DPP4DPP7NR1H3 | |
| SCHEMBL30741110 | 0.87 | PARP1 (0.44) | PARP1NR1H2DPP4DPP7NR1H3 | |
| SCHEMBL874416 | 0.87 | NR1H2 (0.49) | PARP1NR1H2DPP4DPP7NR1H3 | |
| SCHEMBL4325057 | 0.87 | NR1H2 (0.49) | PARP1NR1H2DPP4DPP7NR1H3 | |
| SCHEMBL22285173 | 0.87 | NR1H2 (0.49) | PARP1NR1H2DPP4DPP7NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115557933-B | Bruton tyrosine kinase and mutant degradation agent, composition and application thereof | 杭州和正医药有限公司 | 2024-08-16 | — | — | CN | disclosed |
| CN-115557933-A | Bruton tyrosine kinase and mutant degradation agent, composition and application thereof | 杭州和正医药有限公司 | 2023-01-03 | — | — | CN | disclosed |
| CN-106905245-A | The dibasic pyrimidines of 2,4- | 正大天晴药业集团股份有限公司 | 2017-06-30 | — | — | CN | disclosed |
| CN-103534241-A | Fak inhibitor | CANCER THERAPEUTICS CRC PTY LTD | 2014-01-22 | — | — | CN | disclosed |
| CN-1131222-C | Benzamide derivatives and their use as inhibitors of APOB-100 secretion | GLAXO GROUP LTD (GB) | 2003-12-17 | — | — | CN | disclosed |
| CN-1334808-A | Benzamide derivatives and their use as inhibitors of APOB-100 secretion | GLAXO GROUP LTD (GB) | 2002-02-06 | — | — | CN | disclosed |
| US-6069143-A | Fibrinogen receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2000-05-30 | — | — | US | disclosed |