Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | BLM | P54132 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.55 |
| ▸ | ADORA2B | P29275 | 7/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Furafylline SCHEMBL191214 | 0.73 | MEN1 (1.00) | LMNABLMSMN1; SMN2MEN1CYP1A1 | |
| SCHEMBL1457311 | 0.69 | HTT (0.62) | LMNABLMSMN1; SMN2MEN1CYP1A1 | |
| SCHEMBL23635735 | 0.69 | ADORA2A (0.50) | LMNABLMSMN1; SMN2MEN1CYP1A1 | |
| SCHEMBL2592397 | 0.69 | TSHR (0.66) | LMNABLMSMN1; SMN2MEN1CYP1A1 | |
| SCHEMBL15837498 | 0.68 | TSHR (0.74) | LMNABLMSMN1; SMN2MEN1CYP1A2 | |
| SCHEMBL9392263 | 0.68 | MAPK1 (0.58) | LMNABLMSMN1; SMN2MEN1CYP1A1 | |
| SCHEMBL15749615 | 0.66 | ADORA2A (0.58) | LMNABLMSMN1; SMN2MEN1CYP1A1 | |
| SCHEMBL15749716 | 0.66 | HTT (0.60) | LMNABLMSMN1; SMN2MEN1CYP1A1 | |
| SCHEMBL11279599 | 0.65 | LMNA (0.57) | LMNASMN1; SMN2MEN1MAPK1KMT2A | |
| SCHEMBL9392090 | 0.64 | TSHR (0.50) | LMNABLMSMN1; SMN2MEN1CYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6075029-A | Xanthine modulators of metabolism of cellular P-450 | CELL THERAPEUTICS, INC. (US) | 2000-06-13 | — | — | US | disclosed |