8-Hydroxy-7-Iodo-5-Quinolinesulfonic Acid

8-Hydroxy-7-Iodo-5-Quinolinesulfonic Acid

SCHEMBL8140547

O=S(=O)(O)c1cc(I)c(O)c2ncccc12.[GeH4]

nearest known ligand 0.97

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HIF1A Q16665 4/20 0.62
▸ ALOX15 P16050 4/20 0.62
▸ HPGD P15428 3/20 0.62
▸ ALDH1A1 P00352 3/20 0.62
▸ HSP90AA1 P07900 3/20 0.62
▸ HSD17B10 Q99714 3/20 0.62
▸ KDM4E B2RXH2 2/20 0.62
▸ MEN1 O00255 2/20 0.62
▸ USP2 O75604 2/20 0.62
▸ LMNA P02545 2/20 0.62
▸ TP53 P04637 2/20 0.62
▸ SLC6A2 P23975 2/20 0.62
▸ MAPK1 P28482 2/20 0.62
▸ HTT P42858 2/20 0.62
▸ KMT2A Q03164 2/20 0.62
▸ SMN1; SMN2 Q16637 2/20 0.62
▸ TDP1 Q9NUW8 2/20 0.62
▸ EGFR P00533 1/20 0.62
▸ ERBB2 P04626 1/20 0.62
▸ LCK P06239 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
8-Hydroxy-7-Iodo-5-Quinolinesulfonic Acid SCHEMBL94250 0.98 HIF1A (0.64) HIF1AALOX15HPGDALDH1A1HSP90AA1
8-Hydroxy-7-Iodo-5-Quinolinesulfonic Acid SCHEMBL29385217 0.98 HIF1A (0.64) HIF1AALOX15HPGDALDH1A1HSP90AA1
8-Hydroxy-7-Iodo-5-Quinolinesulfonic Acid SCHEMBL27581572 0.92 HIF1A (0.56) HIF1AALOX15HPGDALDH1A1HSP90AA1
8-Hydroxy-7-Iodo-5-Quinolinesulfonic Acid SCHEMBL4459429 0.91 HIF1A (0.55) HIF1AALOX15HPGDALDH1A1HSP90AA1
SCHEMBL112181 0.87 HIF1A (0.64) HIF1AALOX15HPGDALDH1A1HSP90AA1
SCHEMBL28471201 0.85 HSP90AA1 (0.62) HIF1AALOX15HPGDALDH1A1HSP90AA1
SCHEMBL4461500 0.84 COMT (0.64) HIF1AALOX15HPGDALDH1A1HSP90AA1
SCHEMBL9818532 0.82 HSP90AA1 (0.66) HIF1AALOX15HPGDALDH1A1HSP90AA1
SCHEMBL2981945 0.81 COMT (0.66) HIF1AALOX15HPGDALDH1A1HSP90AA1
SCHEMBL13921640 0.81 COMT (0.66) HIF1AALOX15HPGDALDH1A1HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1129435-C Germanium yeast human diet nutrition additive VIVA AMERICAN MARKETING INC (US) 2003-12-03 — — CN disclosed
US-6017526-A Germanium yeast human diet nutritional supplement VIVA AMERICA MARKETING, INC. (US) 2000-01-25 — — US disclosed
CN-1177301-A Germanium yeast human diet nutritional supplement VIVA AMERICAN MARKETING INC (US) 1998-03-25 — — CN disclosed
EP-0800400-A1 GERMANIUM YEAST HUMAN DIET NUTRITIONAL SUPPLEMENT Viva America Marketing, Inc. (US) 1997-10-15 — — EP disclosed
WO-1997017080-A1 GERMANIUM YEAST HUMAN DIET NUTRITIONAL SUPPLEMENT VIVA AMERICA MARKETING, INC. (US) 1997-05-15 — — WO disclosed
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