8-Hydroxy-7-Iodo-5-Quinolinesulfonic Acid

8-Hydroxy-7-Iodo-5-Quinolinesulfonic Acid

SCHEMBL94250

O=S(=O)(O)c1cc(I)c(O)c2ncccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 4/20 0.64
ALOX15 P16050 4/20 0.64
HPGD P15428 3/20 0.64
ALDH1A1 P00352 3/20 0.64
HSP90AA1 P07900 3/20 0.64
HSD17B10 Q99714 3/20 0.64
KDM4E B2RXH2 2/20 0.64
MEN1 O00255 2/20 0.64
USP2 O75604 2/20 0.64
LMNA P02545 2/20 0.64
TP53 P04637 2/20 0.64
SLC6A2 P23975 2/20 0.64
MAPK1 P28482 2/20 0.64
HTT P42858 2/20 0.64
KMT2A Q03164 2/20 0.64
SMN1; SMN2 Q16637 2/20 0.64
TDP1 Q9NUW8 2/20 0.64
EGFR P00533 1/20 0.64
ERBB2 P04626 1/20 0.64
LCK P06239 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
8-Hydroxy-7-Iodo-5-Quinolinesulfonic Acid SCHEMBL29385217 1.00 HIF1A (0.64) HIF1AALOX15HPGDALDH1A1HSP90AA1
8-Hydroxy-7-Iodo-5-Quinolinesulfonic Acid SCHEMBL8140547 0.98 HIF1A (0.62) HIF1AALOX15HPGDALDH1A1HSP90AA1
8-Hydroxy-7-Iodo-5-Quinolinesulfonic Acid SCHEMBL27581572 0.93 HIF1A (0.56) HIF1AALOX15HPGDALDH1A1HSP90AA1
8-Hydroxy-7-Iodo-5-Quinolinesulfonic Acid SCHEMBL4459429 0.92 HIF1A (0.55) HIF1AALOX15HPGDALDH1A1HSP90AA1
SCHEMBL112181 0.88 HIF1A (0.64) HIF1AALOX15HPGDALDH1A1HSP90AA1
SCHEMBL28471201 0.87 HSP90AA1 (0.62) HIF1AALOX15HPGDALDH1A1HSP90AA1
SCHEMBL4461500 0.86 COMT (0.64) HIF1AALOX15HPGDALDH1A1HSP90AA1
SCHEMBL9818532 0.83 HSP90AA1 (0.66) HIF1AALOX15HPGDALDH1A1HSP90AA1
SCHEMBL13921640 0.82 COMT (0.66) HIF1AALOX15HPGDALDH1A1HSP90AA1
SCHEMBL22802119 0.82 COMT (0.67) HIF1AALOX15HPGDALDH1A1HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1980 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260001943-A1 ANTI-ELASTIN ANTIBODIES AND METHODS OF USE CLEMSON UNIVERSITY RESEARCH FOUNDATION 2026-01-01 US claimed
US-20240228912-A9 COMPOSITION FOR CLEANING SEMICONDUCTOR SUBSTRATE, AND CLEANING METHOD MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2024-07-11 US claimed
CN-116930325-B Electromagnetic ultrasonic composite transducer for metal pipeline defect imaging 哈尔滨工业大学 2024-05-24 CN claimed
US-11975109-B2 Methods for targeted delivery of agents to degraded elastic fibers CLEMSON UNIVERSITY RESEARCH FOUNDATION (US) 2024-05-07 US claimed
US-20240132805-A1 COMPOSITION FOR CLEANING SEMICONDUCTOR SUBSTRATE, AND CLEANING METHOD MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2024-04-25 US claimed
EP-4307348-A1 COMPOSITION FOR CLEANING SEMICONDUCTOR SUBSTRATE, AND CLEANING METHOD MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2024-01-17 EP claimed
CN-117327009-A Crystal compound, preparation method and application 闽都创新实验室 2024-01-02 CN claimed
CN-117015845-A Composition for cleaning semiconductor substrate and cleaning method 三菱瓦斯化学株式会社 2023-11-07 CN claimed
CN-116930325-A Electromagnetic ultrasonic composite transducer for metal pipeline defect imaging 哈尔滨工业大学 2023-10-24 CN claimed
CN-116206209-A Remote sensing monitoring method for permanganate index of river in Zhujiang river basin 苏州天之谋科技有限公司 2023-06-02 CN claimed
US-5399478-A Gelatino-peptizer dispersion includes iodo-substituted 8-hydroxyquinoline EASTMAN KODAK COMPANY (US) 1995-03-21 US claimed
EP-0605355-A1 Oxygen-quenchable phosphorescent materials and their applications in oxygen sensing UNIVERSIDAD DE OVIEDO (ES) 1994-07-06 EP claimed
EP-0506207-A2 Pharmaceutical vehicles for reducing transdermal flux CHEMEX PHARMACEUTICALS, Inc. (US) 1992-09-30 EP claimed
US-4895727-A Using water soluble zinc compound CHEMEX PHARMACEUTICALS, INC. (US) 1990-01-23 US claimed
US-4714614-A PSEUDOMONAS AND FERRIC ION CHELATING AGENT COLORADO STATE UNIVERSITY (US) 1987-12-22 US claimed
EP-0096457-B1 INDIUM COMPLEXES OF SUBSTITUTED 8-HYDROXY-QUINOLINES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE AS ANTIBACTERIAL AGENTS NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1987-03-11 EP claimed
US-4608372-A FUNGICIDES HOFFMANN-LA ROCHE INC. (US) 1986-08-26 US claimed
EP-0046270-B1 NOVEL DERIVATIVES OF BIO-AFFECTING PHENOLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITION CONTAINING THEM INTERx RESEARCH CORPORATION (US) 1986-05-21 EP claimed
EP-0096457-A1 Indium complexes of substituted 8-hydroxy-quinolines, pharmaceutical compositions containing them and their use as antibacterial agents NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1983-12-21 EP claimed
EP-0046270-A1 Novel derivatives of bio-affecting phenolic compounds and pharmaceutical composition containing them INTERx RESEARCH CORPORATION (US) 1982-02-24 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260001943-A1 ANTI-ELASTIN ANTIBODIES AND METHODS OF USE COL2A1, TTI2, CD47 HIF1A 2882/4885ALOX15 2760/4885HPGD 4324/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.