Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.66 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.66 |
| ▸ | COMT | P21964 | 11/20 | 0.60 |
| ▸ | MMP14 | P50281 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | PTPRC | P08575 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.53 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.53 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.53 |
| ▸ | PTPRJ | Q12913 | 1/20 | 0.53 |
| ▸ | DUSP26 | Q9BV47 | 1/20 | 0.53 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.53 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12192929 | 0.89 | HSP90AA1 (0.69) | HSP90AA1HSP90AB1COMTMMP14CYP1A2 | |
| SCHEMBL4461500 | 0.87 | COMT (0.64) | HSP90AA1HSP90AB1COMTCYP1A2HIF1A | |
| 8-Hydroxy-7-Iodo-5-Quinolinesulfonic Acid SCHEMBL29385217 | 0.83 | HIF1A (0.64) | HSP90AA1HSP90AB1COMTMMP14CYP1A2 | |
| SCHEMBL22802119 | 0.83 | COMT (0.67) | HSP90AA1COMTMMP14CYP1A2HIF1A | |
| SCHEMBL2981945 | 0.83 | COMT (0.66) | HSP90AA1HSP90AB1COMTCYP1A2HIF1A | |
| SCHEMBL13921640 | 0.83 | COMT (0.66) | HSP90AA1HSP90AB1COMTCYP1A2HIF1A | |
| 8-Hydroxy-7-Iodo-5-Quinolinesulfonic Acid SCHEMBL94250 | 0.83 | HIF1A (0.64) | HSP90AA1HSP90AB1COMTMMP14CYP1A2 | |
| 8-Hydroxy-7-Iodo-5-Quinolinesulfonic Acid SCHEMBL8140547 | 0.82 | HIF1A (0.62) | HSP90AA1HSP90AB1COMTMMP14CYP1A2 | |
| SCHEMBL6754590 | 0.81 | COMT (0.69) | HSP90AA1HSP90AB1COMTMMP14CYP1A2 | |
| SCHEMBL8883998 | 0.81 | ENPP2 (0.60) | HSP90AA1HSP90AB1COMTCYP1A2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101602724-B | 4,4'-bis(5-sulfo-8-hydroxyl-7-aminoquinoline azo)-3,5,3',5'-tetrabromo-diphenyl ether | UNIV SHANXI DATONG | 2011-05-18 | — | — | CN | disclosed |
| US-5001227-A | Fibre-reactive 1:1 chromium complex azo or azomethine dyes having a bidentate chelating group and a monofunctional neutral ligand | CIBA-GEIGY CORPORATION (US) | 1991-03-19 | — | — | US | disclosed |
| EP-0144776-B1 | FIBRE-REACTIVE CHROMIUM COMPLEXES, THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1989-10-11 | — | — | EP | disclosed |
| EP-0144776-A2 | Fibre-reactive chromium complexes, their preparation and their use | CIBA-GEIGY AG (CH) | 1985-06-19 | — | — | EP | disclosed |