SCHEMBL814070

SCHEMBL814070

CCCCC/C=C\C/C=C\CCCCCCCCF

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 1/20 0.57
ALDH1A1 P00352 4/20 0.55
KDM4E B2RXH2 3/20 0.55
F7 P08709 3/20 0.55
F3 P13726 3/20 0.55
PPARG P37231 2/20 0.55
PPARD Q03181 2/20 0.55
PPARA Q07869 2/20 0.55
FABP3 P05413 2/20 0.55
DUSP3 P51452 1/20 0.55
FAAH O00519 1/20 0.55
PTPN7 P35236 1/20 0.55
FFAR1 O14842 1/20 0.55
LMNA P02545 1/20 0.55
CYP3A4 P08684 1/20 0.55
CYP19A1 P11511 1/20 0.55
FABP4 P15090 1/20 0.55
HPGD P15428 1/20 0.55
ALOX15 P16050 1/20 0.55
TSHR P16473 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12917418 1.00 TRPV1 (0.57) TRPV1ALDH1A1KDM4EF7F3
SCHEMBL28237567 0.93 FAAH (0.58) TRPV1F7F3PPARGPPARD
SCHEMBL28862751 0.93 FAAH (0.58) TRPV1F7F3PPARGPPARD
SCHEMBL28237611 0.93 FAAH (0.58) TRPV1F7F3PPARGPPARD
SCHEMBL815032 0.93 FAAH (0.58) TRPV1F7F3PPARGPPARD
SCHEMBL28052567 0.93 FAAH (0.58) TRPV1F7F3PPARGPPARD
SCHEMBL8661488 0.93 FAAH (0.58) TRPV1F7F3PPARGPPARD
SCHEMBL815030 0.93 FAAH (0.58) TRPV1F7F3PPARGPPARD
Ammonia Solution, Strong SCHEMBL7641977 0.91 FAAH (0.56) TRPV1F7F3PPARGPPARD
SCHEMBL25220064 0.88 FAAH (0.52) TRPV1F7F3PPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2321363-B1 TELECHELIC OLEFIN METATHESIS POLYMERS FROM RENEWABLE FEEDSTOCKS MATERIA INC (US) 2020-04-22 EP disclosed
EP-2046719-B1 RING OPENING CROSS-METATHESIS REACTION OF CYCLIC OLEFINS WITH SEED OILS AND THE LIKE ELEVANCE RENEWABLE SCIENCES (US) 2013-09-04 EP disclosed
US-8324334-B2 Telechelic olefin metathesis polymers from renewable feedstocks MATERIA, INC. (US) 2012-12-04 US disclosed
US-8067623-B2 Producing waxes from soybean oil; ruthenium alkylidene catalytic, simultaneous opening and inserting ELEVANCE RENEWABLE SCIENCES, INC. (US) 2011-11-29 US disclosed
EP-2321363-A1 TELECHELIC OLEFIN METATHESIS POLYMERS FROM RENEWABLE FEEDSTOCKS Materia, Inc. (US) 2011-05-18 EP disclosed
WO-2010021740-A1 TELECHELIC OLEFIN METATHESIS POLYMERS FROM RENEWABLE FEEDSTOCKS MATERIA, INC. (US) 2010-02-25 WO disclosed
EP-2046719-A2 RING OPENING CROSS-METATHESIS REACTION OF CYCLIC OLEFINS WITH SEED OILS AND THE LIKE Elevance Renewable Sciences, Inc. (US) 2009-04-15 EP disclosed
US-20080064891-A1 Ring opening cross-metathesis reaction of cyclic olefins with seed oils and the like WILMAR TRADING PTE LTD (SG) 2008-03-13 US disclosed
WO-2008008440-A2 RING OPENING CROSS-METATHESIS REACTION OF CYCLIC OLEFINS WITH SEED OILS AND THE LIKE ELEVANCE RENEWABLE SCIENCES, INC. (US) 2008-01-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080064891-A1 Ring opening cross-metathesis reaction of cyclic olefins with seed oils and the like SQLE, COASY, ALOX12 TRPV1 3404/4885ALDH1A1 1251/4885KDM4E 4258/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.