Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | GALR2 | O43603 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | KMT5A | Q9NQR1 | 1/20 | 0.48 |
| ▸ | GALR1 | P47211 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8133672 | 1.00 | CCR4 (0.56) | CCR4KDM4EALDH1A1MAPTNPSR1 | |
| SCHEMBL13757369 | 0.88 | KDM4E (0.62) | CCR4KDM4EALDH1A1MAPTPOLB | |
| SCHEMBL13728425 | 0.84 | CCR4 (0.52) | CCR4KDM4EALDH1A1MAPTNPSR1 | |
| SCHEMBL13728319 | 0.84 | KDM4E (0.53) | CCR4KDM4EALDH1A1MAPTNPSR1 | |
| SCHEMBL30547003 | 0.78 | KDM4E (0.58) | CCR4KDM4EALDH1A1MAPTNPSR1 | |
| SCHEMBL6512019 | 0.76 | KDM4E (0.86) | KDM4EALDH1A1MAPTNPSR1POLB | |
| SCHEMBL5873086 | 0.76 | NCF1 (0.63) | KDM4EALDH1A1MAPTNPSR1KMT2A | |
| SCHEMBL18893696 | 0.75 | EGFR (0.49) | CCR4KDM4EALDH1A1MAPTNPSR1 | |
| SCHEMBL5036263 | 0.74 | NCF1 (0.61) | KDM4EALDH1A1MAPTNPSR1KMT2A | |
| SCHEMBL8145017 | 0.74 | KDM4E (0.46) | CCR4KDM4EALDH1A1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009005677-A2 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2009-01-08 | — | — | WO | disclosed |