Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.51 |
| ▸ | TUBB | P07437 | 1/20 | 0.51 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.51 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.51 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.51 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.51 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.51 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.51 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.51 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.51 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.51 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.51 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.51 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5036263 | 0.99 | NCF1 (0.61) | NCF1ALDH1A1KDM4EKMT2ATSHR | |
| Hydrochloric Acid SCHEMBL6377887 | 0.97 | NCF1 (0.59) | NCF1ALDH1A1KDM4EKMT2ATSHR | |
| SCHEMBL5402285 | 0.90 | NCF1 (0.58) | NCF1ALDH1A1KDM4EKMT2ATSHR | |
| SCHEMBL5405102 | 0.88 | NCF1 (0.56) | NCF1ALDH1A1KDM4EKMT2ATSHR | |
| SCHEMBL5033327 | 0.86 | NCF1 (0.51) | NCF1ALDH1A1KDM4EKMT2ATUBB4A | |
| SCHEMBL5405430 | 0.85 | NCF1 (0.50) | NCF1ALDH1A1KDM4EKMT2ATSHR | |
| SCHEMBL5036246 | 0.85 | NCF1 (0.50) | NCF1ALDH1A1KDM4EKMT2ATSHR | |
| SCHEMBL5412027 | 0.85 | NCF1 (0.55) | NCF1ALDH1A1KDM4EKMT2ATSHR | |
| Hydrochloric Acid SCHEMBL5042719 | 0.85 | NCF1 (0.50) | NCF1ALDH1A1KDM4EKMT2ATUBB4A | |
| Hydrochloric Acid SCHEMBL5040490 | 0.84 | NCF1 (0.49) | NCF1ALDH1A1KDM4EKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7012073-B2 | Quinoline derivatives | HOFFMANN-LA ROCHE INC. (US) | 2006-03-14 | — | — | US | disclosed |
| US-20040259858-A1 | Quinoline derivatives | KLUG MICHAEL G (US) | 2004-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040259858-A1 | Quinoline derivatives | RAB1A, GLS, REN | NCF1 1277/4885ALDH1A1 700/4885KDM4E 1521/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.