SCHEMBL814191

SCHEMBL814191

C[SiH](C)[Zr](C1c2ccccc2-c2ccccc21)C1c2ccccc2-c2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 2/20 0.41
HTR2A P28223 1/20 0.37
HDAC3 O15379 1/20 0.36
HDAC4 P56524 1/20 0.36
HDAC7 Q8WUI4 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
HDAC9 Q9UKV0 1/20 0.36
HDAC5 Q9UQL6 1/20 0.36
NCOR2 Q9Y618 1/20 0.36
POLB P06746 2/20 0.35
ACHE P22303 3/20 0.34
CHRM2 P08172 1/20 0.34
HTR1A P08908 1/20 0.34
ADRA2A P08913 1/20 0.34
CHRM1 P11229 1/20 0.34
DRD1 P21728 1/20 0.34
SLC6A2 P23975 1/20 0.34
SLC6A4 P31645 1/20 0.34
ADRA1A P35348 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL906469 0.98 GPR3 (0.40) GPR3HTR2AHDAC3HDAC4HDAC7
Chloromethane SCHEMBL7037925 0.96 GPR3 (0.39) GPR3HTR2AHDAC3HDAC4HDAC7
SCHEMBL814590 0.83 GPR3 (0.31) GPR3
SCHEMBL8202195 0.82 GPR3 (0.31) GPR3
Hydrochloric Acid SCHEMBL1978361 0.82 GPR3 (0.30) GPR3
SCHEMBL6917289 0.79 GPR3 (0.31) GPR3HTR2ACHRM2CHRM1SLC6A2
SCHEMBL7066602 0.76 GPR3 (0.35) GPR3HTR2AHDAC3HDAC4HDAC7
SCHEMBL7103508 0.73 GPR3 (0.46) GPR3HTR2AHDAC3HDAC4HDAC7
SCHEMBL7195132 0.73 ACHE (0.42) ACHECHRM2HTR1AADRA2ACHRM1
Hydrochloric Acid SCHEMBL10181364 0.72 ACHE (0.41) ACHECHRM2HTR1AADRA2ACHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 140 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0524624-B1 Use of organometallic flurorenyl compounds. PHILLIPS PETROLEUM CO (US) 2002-05-15 EP claimed
EP-0889911-B1 METALLOCENE COCATALYST DOW CHEMICAL CO (US) 2000-11-02 EP claimed
EP-0615981-B1 Supported catalyst system, its preparation and its use in olefin polymerisation TARGOR GMBH (DE) 1998-05-06 EP claimed
EP-0610852-B1 Process for preparing cyclo-olefin polymers HOECHST AG (DE) 1997-05-07 EP claimed
US-11618791-B2 Systems and methods for producing a supported catalyst EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-04-04 US disclosed
EP-4065277-A1 SYSTEMS AND METHODS FOR PRODUCING A SUPPORTED CATALYST ExxonMobil Chemical Patents Inc. (US) 2022-10-05 EP disclosed
WO-2021108049-A1 SYSTEMS AND METHODS FOR PRODUCING A SUPPORTED CATALYST EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-06-03 WO disclosed
US-20210155723-A1 Systems and Methods for Producing a Supported Catalyst EXXONMOBIL CHEMICAL PATENTS INC (US) 2021-05-27 US disclosed
EP-2872539-B1 INCREASED POLYMER MELT FLOW RATIO VIA FEED OF A SUPPORTED CATALYST SATURATED WITH A SELECTED LIQUID AGENT UNIVATION TECH LLC (US) 2020-12-09 EP disclosed
US-9512254-B2 Increased polymer melt flow ratio via feed of a supported catalyst saturated with a selected liquid agent UNIVATION TECHNOLOGIES, LLC (US) 2016-12-06 US disclosed
EP-1716183-B1 DE-FOAMING SPRAY DRIED CATALYST SLURRIES UNIVATION TECH LLC (US) 2016-04-13 EP disclosed
EP-2872539-A1 INCREASED POLYMER MELT FLOW RATIO VIA FEED OF A SUPPORTED CATALYST SATURATED WITH A SELECTED LIQUID AGENT Univation Technologies, LLC (US) 2015-05-20 EP disclosed
WO-2003064435-A1 POLYMERIZATION CATALYST ACTIVATOR COMPLEXES AND THEIR USE IN A POLYMERIZATION PROCESS UNIVATION TECHNOLOGIES, LLC (US) 2003-08-07 WO disclosed
EP-0530908-B2 Process for the preparation of a bridged metallocene compound as well as a catalyst component and a process for the polymerization of olefins DSM NV (NL) 2003-06-04 EP disclosed
EP-0927201-A1 CATALYST SYSTEM FOR (CO)POLYMERIZATION OF OLEFINS AND PROCESS FOR THE PREPARATION OF OLEFIN (CO)POLYMERS USING THE CATALYST SYSTEM Hyundai Petrochemical Co., Ltd. (KR) 1999-07-07 EP disclosed
EP-0530908-B1 Process for the preparation of a bridged metallocene compound as well as a catalyst component and a process for the polymerization of olefins DSM NV (NL) 1999-04-21 EP disclosed
WO-1998009996-A1 CATALYST SYSTEM FOR (CO)POLYMERIZATION OF OLEFINS AND PROCESS FOR THE PREPARATION OF OLEFIN (CO)POLYMERS USING THE CATALYST SYSTEM HYUNDAI PETROCHEMICAL CO., LTD. (KR) 1998-03-12 WO disclosed
US-5646083-A Process for the preparation of a bridged metallocene compound as well as a catalyst component and a process for the polymerization of olefins DSM N.V. (NL) 1997-07-08 US disclosed
EP-0697436-A1 Thermoplastic compositions of atactic and syndiotactic polypropylene Montell Technology Company bv (NL) 1996-02-21 EP disclosed
EP-0530908-A1 Process for the preparation of a bridged metallocene compound as well as a catalyst component and a process for the polymerization of olefins DSM N.V. (NL) 1993-03-10 EP disclosed