Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.49 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22922181 | 0.87 | CYP4F2 (0.59) | ALDH1A1TSHRHSD17B10CYP4F2CYP4A11 | |
| SCHEMBL14733281 | 0.86 | CYP4F2 (0.49) | ALDH1A1TSHRHSD17B10CYP4F2CYP4A11 | |
| SCHEMBL12339923 | 0.85 | SMN1; SMN2 (0.45) | ALDH1A1MAPK1NPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL5593638 | 0.84 | KDM4E (0.49) | ALDH1A1MAPK1NPC1SMN1; SMN2HPGD | |
| SCHEMBL10729278 | 0.83 | CYP4F2 (0.68) | ALDH1A1MAPK1NPC1SMN1; SMN2HPGD | |
| SCHEMBL10869549 | 0.83 | MMP8 (0.41) | ALDH1A1MAPK1NPC1SMN1; SMN2HPGD | |
| SCHEMBL10869547 | 0.83 | MMP8 (0.41) | ALDH1A1MAPK1NPC1SMN1; SMN2HPGD | |
| SCHEMBL7360766 | 0.81 | CYP4F2 (0.59) | ALDH1A1MAPK1NPC1SMN1; SMN2HPGD | |
| SCHEMBL9718461 | 0.81 | TDP1 (0.50) | ALDH1A1SMN1; SMN2HPGDKDM4ECYP4F2 | |
| SCHEMBL15080669 | 0.81 | CYP4F2 (0.49) | ALDH1A1KDM4ECYP4F2CYP4A11MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6069149-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | TERUMO KABUSHIKI KAISHA (JP) | 2000-05-30 | — | — | US | disclosed |
| EP-0894797-A1 | NOVEL AMIDE DERIVATIVES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | TERUMO KABUSHIKI KAISHA (JP) | 1999-02-03 | — | — | EP | disclosed |
| CN-1079648-A | Preparation contains the method for the pharmaceutical composition of imidazolyl-alkenoic acids | SMITHKLINE BEECHAM CORP (US) | 1993-12-22 | — | — | CN | disclosed |
| CN-1048039-A | Imidazolyl-alkenoic acids | SMITHKLINE BEECHAM CORP (US) | 1990-12-26 | — | — | CN | disclosed |