Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.59 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | GFER | P55789 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4113212 | 0.85 | CYP4F2 (0.76) | CYP4F2CYP4A11ALDH1A1HPGDGAA | |
| SCHEMBL512626 | 0.81 | CYP4Z1 (0.55) | CYP4F2CYP4A11ALDH1A1HPGDGAA | |
| SCHEMBL11234424 | 0.81 | KMT2A (0.53) | ALDH1A1HPGDGAASMN1; SMN2TSHR | |
| SCHEMBL8142192 | 0.81 | ALDH1A1 (0.50) | CYP4F2CYP4A11ALDH1A1HPGDGAA | |
| SCHEMBL17653822 | 0.81 | CYP4F2 (0.51) | CYP4F2CYP4A11ALDH1A1HPGDGAA | |
| SCHEMBL17114422 | 0.80 | CYP4F2 (0.50) | CYP4F2CYP4A11ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL10611271 | 0.79 | ALDH1A1 (0.56) | ALDH1A1HPGDGAASMN1; SMN2TSHR | |
| SCHEMBL2568449 | 0.79 | HDAC1 (0.58) | ALDH1A1TSHRMAPK1HDAC1HDAC6 | |
| SCHEMBL7472261 | 0.79 | CYP4F2 (0.62) | CYP4F2CYP4A11ALDH1A1HPGDGAA | |
| SCHEMBL11031784 | 0.79 | ALDH1A1 (0.44) | ALDH1A1HPGDGAASMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117255814-A | Catechol-containing film material | 米塞尔聚合物公司 | 2023-12-19 | — | — | CN | disclosed |
| EP-1849796-B1 | ANTI-PENICILLIN RESISTANT PNEUMOCOCCI AGENT AND NOVEL 16-MEMBERED RING MACROLIDE DERIVATIVE | MICROBIAL CHEM RES FOUND (JP) | 2014-11-05 | — | — | EP | disclosed |
| US-8507453-B2 | Anti-penicillin resistant pneumococci agent and novel 16-membered macrolide derivative | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2013-08-13 | — | — | US | disclosed |
| US-8507453-B2 | Anti-penicillin resistant pneumococci agent and novel 16-membered macrolide derivative | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2013-08-13 | — | — | US | disclosed |
| CN-101400657-B | Polycyclic cinnamamide derivative | ESAI R & D MAN CO LTD | 2012-05-30 | — | — | CN | disclosed |
| US-20120015896-A1 | Anti-Penicillin Resistant Pneumococci Agent and Novel 16-Membered Macrolide Derivative | MICROBIAL CHEMISTRY RESEARCH FOUNDATION | 2012-01-19 | — | — | US | disclosed |
| US-20120015896-A1 | Anti-Penicillin Resistant Pneumococci Agent and Novel 16-Membered Macrolide Derivative | MICROBIAL CHEMISTRY RESEARCH FOUNDATION | 2012-01-19 | — | — | US | disclosed |
| US-8053418-B2 | Anti-penicillin resistant pneumococci agent and novel 16-membered macrolide derivative | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2011-11-08 | — | — | US | disclosed |
| US-8053418-B2 | Anti-penicillin resistant pneumococci agent and novel 16-membered macrolide derivative | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2011-11-08 | — | — | US | disclosed |
| CN-101400657-A | Polycyclic cinnamamide derivative | ESAI R & D MAN CO LTD (JP) | 2009-04-01 | — | — | CN | disclosed |
| US-20080300388-A1 | Anti-Penicillin Resistant Pneumococci Agent and Novel 16-Membered Macrolide Derivative | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2008-12-04 | — | — | US | disclosed |
| US-20080300388-A1 | Anti-Penicillin Resistant Pneumococci Agent and Novel 16-Membered Macrolide Derivative | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2008-12-04 | — | — | US | disclosed |
| US-7250525-B2 | Stilbene derivatives and their use for binding and imaging amyloid plaques | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2007-07-31 | — | — | US | disclosed |
| US-6458796-B1 | METHOD OF TREATING CARDIOVASCULAR DISORDERS, THROMBOEMBOLIC DISORDERS AND ISCHAEMIAS, AND UROGENITAL SYSTEM DISORDERS, COMPRISING ADMINISTERING TO MAMMALS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-10-01 | — | — | US | disclosed |
| US-4778834-A | COATING WITH SILICEOUS MATERIAL AND ORGANOSILANE, THEN POLYMERIZATION | STERLING DRUG INC. (US) | 1988-10-18 | — | — | US | disclosed |
| US-4439554-A | DENTISTRY, ORTHOPEDICS | AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (US) | 1984-03-27 | — | — | US | disclosed |
| US-4390714-A | DENTISTRY | AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (US) | 1983-06-28 | — | — | US | disclosed |
| US-4243763-A | DENTISTRY | AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (US) | 1981-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120015896-A1 | Anti-Penicillin Resistant Pneumococci Agent and Novel 16-Membered Macrolide Derivative | PWWP2B, BRWD1, BAZ1A | CYP4F2 4616/4885CYP4A11 3942/4885ALDH1A1 4196/4885 |
| US-20080300388-A1 | Anti-Penicillin Resistant Pneumococci Agent and Novel 16-Membered Macrolide Derivative | PWWP2B, BRWD1, BAZ1A | CYP4F2 4616/4885CYP4A11 3942/4885ALDH1A1 4196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.