SCHEMBL8142452

SCHEMBL8142452

Brc1ccc(Cc2ccc(I)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
APP P05067 2/20 0.57
TAAR1 Q96RJ0 3/20 0.43
HTR2A P28223 1/20 0.42
CYP2A6 P11509 1/20 0.42
IDO1 P14902 4/20 0.41
CYP3A4 P08684 2/20 0.41
HRH3 Q9Y5N1 1/20 0.41
HTR1D P28221 1/20 0.39
EPHX2 P34913 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3334615 0.86 CYP2A6 (0.57) TAAR1HTR2ACYP2A6IDO1CYP3A4
SCHEMBL5491719 0.86 CYP3A4 (0.50) APPIDO1CYP3A4
SCHEMBL24146 0.83
SCHEMBL455656 0.83 CYP2A6 (0.61) APPTAAR1HTR2ACYP2A6
SCHEMBL8068361 0.83 CYP2A6 (0.61) APPTAAR1HTR2ACYP2A6
SCHEMBL15026028 0.80 APP (0.53) APPTAAR1HTR2A
SCHEMBL668783 0.78 APP (0.68) APPIDO1CYP3A4
SCHEMBL9305877 0.78 CYP3A4 (0.44) APPIDO1CYP3A4HRH3
SCHEMBL16848643 0.78 CYP3A4 (0.44) APPIDO1CYP3A4HRH3
Fluoride SCHEMBL5504537 0.77 CYP2A6 (0.53) APPTAAR1HTR2ACYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6034206-A POLYANILINES; HEAT, CHEMICAL AND SOLVENT RESISTANCE TOSOH CORPORATION (JP) 2000-03-07 US disclosed