Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 9/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | GRM6 | O15303 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5864698 | 0.94 | GAA (0.68) | GAAMAPK1MAPTALDH1A1HSD17B10 | |
| SCHEMBL3113232 | 0.83 | GAA (0.66) | GAAMAPK1MAPTALDH1A1HSD17B10 | |
| SCHEMBL1564819 | 0.81 | MAPT (0.59) | GAAMAPK1MAPTALDH1A1HSD17B10 | |
| SCHEMBL5864713 | 0.81 | GAA (0.63) | GAAMAPK1MAPTALDH1A1HSD17B10 | |
| SCHEMBL5422196 | 0.78 | ALOX15 (0.51) | GAAMAPK1MAPTALDH1A1HSD17B10 | |
| SCHEMBL5865211 | 0.76 | ALOX15 (0.56) | GAAMAPTALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL1973680 | 0.76 | GAA (1.00) | GAAMAPK1MAPTALDH1A1HSD17B10 | |
| SCHEMBL23827481 | 0.76 | GAA (0.56) | GAAMAPK1MAPTALDH1A1HSD17B10 | |
| SCHEMBL1973534 | 0.76 | GAA (0.56) | GAAMAPK1MAPTALDH1A1HSD17B10 | |
| SCHEMBL5864678 | 0.75 | GAA (0.59) | GAAMAPK1MAPTALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991653-A1 | NOVEL COMPOUNDS | Astra Pharmaceuticals Limited (GB) | 2000-04-12 | — | — | EP | disclosed |
| WO-1998054190-A1 | NOVEL COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1998-12-03 | — | — | WO | disclosed |