⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21049503 | 0.81 | LMNA (0.37) | — | |
| SCHEMBL21049520 | 0.79 | — | — | |
| SCHEMBL23526614 | 0.79 | — | — | |
| SCHEMBL16612488 | 0.78 | — | — | |
| SCHEMBL704960 | 0.77 | — | — | |
| SCHEMBL704276 | 0.77 | — | — | |
| SCHEMBL3240183 | 0.74 | LMNA (0.31) | — | |
| SCHEMBL3242432 | 0.74 | LMNA (0.31) | — | |
| SCHEMBL3234192 | 0.74 | LMNA (0.31) | — | |
| SCHEMBL3239536 | 0.74 | LMNA (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2271682-B1 | STYRENE-BUTADIENE POLYMERS WITH STYRENE GRADIENT AND METHODS OF MAKING THE SAME | TRINSEO EUROPE GMBH (CH) | 2016-04-20 | — | — | EP | disclosed |
| US-8053542-B2 | Styrene-butadiene polymers with styrene gradient and methods of making the same | STYRON EUROPE GMBH (CH) | 2011-11-08 | — | — | US | disclosed |
| US-20110178256-A1 | STYRENE-BUTADIENE POLYMERS WITH STYRENE GRADIENT AND METHODS OF MAKING THE SAME | TRINSEO EUROPE GMBH (CH) | 2011-07-21 | — | — | US | disclosed |
| EP-2271682-A2 | STYRENE-BUTADIENE POLYMERS WITH STYRENE GRADIENT AND METHODS OF MAKING THE SAME | Styron Europe GmbH (CH) | 2011-01-12 | — | — | EP | disclosed |
| WO-2009134665-A2 | STYRENE-BUTADIENE POLYMERS WITH STYRENE GRADIENT AND METHODS OF MAKING THE SAME | DOW GLOBAL TECHNOLOGIES INC. (US) | 2009-11-05 | — | — | WO | disclosed |