Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL813872 | 0.89 | HPGD (0.45) | ALDH1A1HPGDMAPTMEN1ALOX15 | |
| SCHEMBL814053 | 0.87 | ALDH1A1 (0.33) | ALDH1A1HPGDMAPTMEN1ALOX15 | |
| SCHEMBL814181 | 0.84 | ALDH1A1 (0.40) | ALDH1A1HPGDMAPTALOX15TSHR | |
| SCHEMBL814097 | 0.82 | MEN1 (0.43) | ALDH1A1HPGDMAPTMEN1ALOX15 | |
| SCHEMBL813913 | 0.82 | ALDH1A1 (0.43) | ALDH1A1MAPTALOX15TSHR | |
| SCHEMBL813780 | 0.81 | ALDH1A1 (0.41) | ALDH1A1HPGDMAPTMEN1MAPK1 | |
| SCHEMBL814526 | 0.81 | MAPT (0.36) | ALDH1A1HPGDMAPTMEN1ALOX15 | |
| SCHEMBL12460048 | 0.79 | RAB9A (0.35) | ALDH1A1HPGDMAPTALOX15TSHR | |
| SCHEMBL813713 | 0.76 | MAPT (0.34) | ALDH1A1MAPTMEN1ALOX15TSHR | |
| SCHEMBL814091 | 0.75 | PSMB5 (0.36) | ALDH1A1HPGDMAPTALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1789459-B1 | POLYOLEFINS | INEOS SALES UK LTD (GB) | 2014-04-30 | — | — | EP | disclosed |
| US-8067328-B2 | Polymerisation and oligomerisation catalysts | INEOS EUROPE LIMITED (GB) | 2011-11-29 | — | — | US | disclosed |
| US-8067328-B2 | Polymerisation and oligomerisation catalysts | INEOS EUROPE LIMITED (GB) | 2011-11-29 | — | — | US | disclosed |
| US-7989565-B2 | Polyolefins | INEOS EUROPE LIMITED (GB) | 2011-08-02 | — | — | US | disclosed |
| US-7989565-B2 | Polyolefins | INEOS EUROPE LIMITED (GB) | 2011-08-02 | — | — | US | disclosed |
| US-20090124487-A1 | Polyolefins | BARCLAYS BANK PLC (GB) | 2009-05-14 | — | — | US | disclosed |
| US-20090124487-A1 | Polyolefins | BARCLAYS BANK PLC (GB) | 2009-05-14 | — | — | US | disclosed |
| US-20070207918-A1 | Polymerisation and Oligomerisation Catalysts | INEOS SALES (UK) LIMITED (GB) | 2007-09-06 | — | — | US | disclosed |
| US-20070207918-A1 | Polymerisation and Oligomerisation Catalysts | INEOS SALES (UK) LIMITED (GB) | 2007-09-06 | — | — | US | disclosed |
| US-7229943-B2 | Polymerisation and oligomerisation catalysts | INNOVENE EUROPE LIMITED (GB) | 2007-06-12 | — | — | US | disclosed |
| US-7229943-B2 | Polymerisation and oligomerisation catalysts | INNOVENE EUROPE LIMITED (GB) | 2007-06-12 | — | — | US | disclosed |